Results 51 to 60 of about 563,981 (384)

miRNAs as Regulators of Antidiabetic Effects of Fucoidans [PDF]

, 2019
open access articleDiabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene ...
Arroo, R. R. J., El-Seed, Hesham, Ismail, Amin, Lai, Shanshan, Liu, Dan, Wu, Desheng, Xiao, Jianbo, Zhao, Chao, Zou, Xiaobo   +8 more
core   +1 more source

Synergic microRNAs suppress human glioblastoma progression by modulating clinically relevant targets

Molecular Therapy: Nucleic Acids
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by therapy-resistant glioma stem-like cells (GSCs) and extensive infiltration into surrounding brain tissue.
Silvia Rancati, Rui C. Pereira, Michele Schlich, Stefania Sgroi, Silvia Beatini, Letizia La Rosa, Lidia Giantomasi, Roberta Pelizzoli, Clarissa Braccia, Andrea Di Fonzo, Carlotta Spattini, Kiril Tuntevski, Amanda Lo Van, Meritxell Pons-Espinal, Annalisa Palange, Adriana Bajetto, Antonio Daga, Andrea Armirotti, Tullio Florio, Paolo Decuzzi, Davide De Pietri Tonelli   +20 more
doaj   +1 more source

Role of Circulating Exosomal miRNA-3976 in Early Diabetic Retinopathy

International Journal of Nanomedicine, 2023
Songtao Yang,1,2 Jiaoyue Zhang,1,2 Tianshu Zeng,1,2 Juan Zheng,1,2 Jie Min,1,2 Lulu Chen1,2 1Department of Endocrinology, Union Hospital, Huazhong University of Science and Technology Tongji Medical College, Wuhan, Hubei, People’s Republic of China ...
Yang S, Zhang J, Zeng T, Zheng J, Min J, Chen L   +5 more
doaj  

Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells

Journal of Extracellular Vesicles, 2020
Mast cells (MCs) are known to participate in a variety of patho-physiological processes depending largely on the intragranular mediators and the production of cytokines and chemokines during degranulation. Recently, extracellular vesicles (EVs) have been
Yuting Liang, Sheng Huang, Longwei Qiao, Xia Peng, Chong Li, Kun Lin, Guogang Xie, Jia Li, Lihui Lin, Yue Yin, Huanjin Liao, Qian Li, Li Li   +12 more
doaj   +1 more source

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA, CARBONE, Antonio, DELLA ROCCA, Carlo, DI CARLO, ANGELINA, FAZI, Francesco, PALLESCHI, GIOVANNI, PASTORE, ANTONIO LUIGI, PETROZZA, Vincenzo, PORTA, NATALE   +8 more
core   +2 more sources

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

Nature Communications, 2013
Exosomes are released by most cells to the extracellular environment and are involved in cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs (miRNAs) and other non-coding RNAs that can be functionally transferred to ...
Carolina Villarroya-Beltri, Cristina Gutiérrez-Vázquez, F. Sánchez-Cabo, Daniel Perez-Hernandez, Jesús Vázquez, N. Martín-Cófreces, D. J. Martínez-Herrera, A. Pascual-Montano, M. Mittelbrunn, F. Sánchez‐Madrid   +9 more
semanticscholar   +1 more source

Plasma Extracellular Vesicle miRNA Profiles Distinguish Chronic Obstructive Pulmonary Disease Exacerbations and Disease Severity

International Journal of COPD, 2022
Hannah E O’Farrell, Rayleen V Bowman, Kwun M Fong, Ian A Yang Faculty of Medicine, the University of Queensland, Brisbane, QLD, AustraliaCorrespondence: Hannah E O’Farrell, Faculty of Medicine, the University of Queensland, Brisbane, QLD, Australia, Tel +
O'Farrell HE, Bowman RV, Fong KM, Yang IA   +3 more
doaj  

Principles of microRNA regulation of a human cellular signaling network [PDF]

, 2006
MicroRNAs (miRNAs) are endogenous 22-nucleotide RNAs, which suppress gene expression by selectively binding to the 3-noncoding region of specific message RNAs through base-pairing.
Edwin Wang, Enrico O Purisima, Kharchenko P, Qinghua Cui, Zhenbao Yu   +4 more
core   +3 more sources

Comprehensive Analysis of a Competing Endogenous RNA Co-Expression Network in Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2023
Jingwei Wang,1,2,* Bowen Xia,3,* Ruimin Ma,1 Qiao Ye1,2 1Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Occupational Medicine and Toxicology ...
Wang J, Xia B, Ma R, Ye Q
doaj  

A Collection of Pre-mRNA Splicing Mutants in Arabidopsis thaliana

G3: Genes, Genomes, Genetics, 2020
To investigate factors influencing pre-mRNA splicing in plants, we conducted a forward genetic screen using an alternatively-spliced GFP reporter gene in Arabidopsis thaliana.
Tatsuo Kanno, Peter Venhuizen, Ming-Tsung Wu, Phebe Chiou, Chia-Liang Chang, Maria Kalyna, Antonius J. M. Matzke, Marjori Matzke   +7 more
doaj   +1 more source