Results 181 to 190 of about 21,203 (224)

Unique Features of Melanoma Risk and Diagnosis in Red-Haired Populations. [PDF]

Int J Mol Sci
Ebrahimi KR, Ostrowski SM, Fisher DE.
europepmc   +1 more source

Ozone exposure promotes melanogenesis through MAPK-dependent oxidative stress signaling: attenuation by resveratrol in zebrafish and melanoma cells. [PDF]

Am J Cancer Res
Lee CH, Chang CJ, Liu WT, Chen PH, Wang CC.   +4 more
europepmc   +1 more source

Mitophagy-driven immune evasion in skin cancer: multidimensional regulatory networks and context-dependent therapeutic strategies-a narrative review. [PDF]

Front Immunol
Lv J, Liu G.
europepmc   +1 more source

Transcriptome Analysis of Linalool-Induced Hypopigmentation in B16 Melanoma Cells. [PDF]

Int J Mol Sci
Villareal MO, Isoda H.
europepmc   +1 more source

MITF in Normal Melanocytes, Cutaneous and Uveal Melanoma: A Delicate Balance [PDF]

International Journal of Molecular Sciences, 2022
Microphthalmia-associated transcription factor (MITF) is an important regulator of melanogenesis and melanocyte development. Although it has been studied extensively in cutaneous melanoma, the role of MITF in uveal melanoma (UM) has not been explored in ...
Thomas Strub, Maria Chiara Gelmi, Laurien E Houtzagers   +2 more
exaly   +2 more sources

Frequent Mutations in the MITF Pathway in Melanoma [PDF]

Pigment Cell and Melanoma Research, 2009
SummaryMicrophthalmia‐associated transcription factor (MITF) is involved in melanocyte cell development, pigmentation and neoplasia. To determine whether MITF is somatically mutated in melanoma, we compared the sequence of MITF from primary and metastatic lesions to patient‐matched normal DNA.
Todd Prickett, William J Pavan, Stacie K Loftus   +2 more
exaly   +3 more sources

MITF: A Stream Flowing for Pigment Cells [PDF]

Pigment Cell & Melanoma Research, 2000
Microphthalmia‐associated t ranscription f actor (MITF) is a transcription factor with a basic‐helix‐loop‐helix‐leucine zipper (bHLHZip) structure. Mutations of the MITF gene cause a variety of phenotypes, most notably in pigmented cells, in several species. In humans, haploinsufficiency of MITF causes Waardenburg syndrome type 2, while a
Masayoshi Tachibana, M Tachibana
exaly   +3 more sources

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Genomic analysis of the Microphthalmia locus and identification of the MITF-J/Mitf-J isoform

Gene, 2005
The deafness-pigmentary disorder Waardenburg Syndrome Type 2 is caused by mutations in the human Microphthalmia-associated transcription factor (MITF) gene. Multiple related deafness-pigmentary disorders result from mutations in genes that regulate MITF expression or its activity.
Christine L, Hershey, David E, Fisher
openaire   +2 more sources

MITF, the Janus Transcription Factor of Melanoma

Future Oncology, 2013
Current models of melanoma propose that transition from the proliferative to the invasive stages of tumor development involves a dynamic and reversible switch in cell phenotype. The almost mutually exclusive proliferative and invasive phenotypes are defined by distinct gene expression signatures, which are themselves controlled by the level of ...
Koludrovic, Dana, Davidson, Irwin
openaire   +2 more sources

Mitf Is Expressed in Osteoclast Progenitors in Vitro

Experimental Cell Research, 2000
Microphthalmia mutant (mi/mi) mice reveal defects in osteoclastogenesis and exhibit osteopetrosis. However, there have been no studies to test the importance of Mitf in in vitro osteoclastogenesis using the cells derived from mi/mi mice. Therefore, we investigated in vitro osteoclastogenesis using the cells derived from mi/mi mice. We cocultured spleen
N, Kawaguchi, M, Noda
openaire   +2 more sources