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A Dominant Negative Mutant of Microphthalmia Transcription Factor (MITF) Lacking Two Transactivation Domains Suppresses Transcription Mediated by Wild Type MITF and a Hyperactive MITF Derivative

Pigment Cell Research, 2004
Microphthalmia transcription factor (MITF) positively regulates transcription of differentiation‐related genes in several cell lineages, including melanocytes. Recent data also indicate a new important role for MITF as a factor that appears to be required for survival of melanoma cells, suggesting a possibility that abrogation of MITF function in ...
Jiri, Vachtenheim, Blanka, Drdová
openaire   +2 more sources

A picture of Mitf in melanoma immortality

Oncogene, 2011
The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senescence by regulating genes implicated in S-phase ...
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MITF

2007
Heinz Arnheiter   +8 more
openaire   +2 more sources

MITF pathway mutations in melanoma

Pigment Cell & Melanoma Research, 2009
Satoru, Yokoyama   +2 more
openaire   +2 more sources

NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism

Cell, 2021
Jennifer Allouche   +2 more
exaly  

MITF Positivity in Atypical Fibroxanthoma

The American Journal of Dermatopathology, 2016
Ben, Tallon, Trevor W, Beer
openaire   +2 more sources

MITF in Normal Melanocytes, Cutaneous and Uveal Melanoma: A Delicate Balance

International Journal of Molecular Sciences, 2022
Maria Chiara Gelmi   +2 more
exaly  

An exploitable Achilles heel of MITF?

Cell Research, 2022
Carolina Silva, Ze’ev A. Ronai
openaire   +2 more sources

MITF – past, present and future

Pigment Cell & Melanoma Research, 2010
openaire   +2 more sources

BRCA1 is a new MITF target gene

Pigment Cell & Melanoma Research, 2011
Laurent, Beuret   +6 more
openaire   +2 more sources

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