Results 111 to 120 of about 17,423 (206)

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, EarlyView.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source

DcH3.3 and DcNAC1 Regulate the Expression of UGT73A93 Involved in the Changes in Flower Colour and Fungal Resistance in Carnation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Carnation (Dianthus caryophyllus) contains abundant flavonoid glycosides (FGs), which are important natural functional and colour components. However, there are few reports on the modification of UDP‐glycosyltransferases (UGTs) in relation to flavonoids in carnation.
Xuhong Zhou, Qirui Xiong, Yue Zhang, Xiumei Yang, Siyuan Zhang, Yanxia Tao, Xiaomi Yang   +6 more
wiley   +1 more source

The genome of Phlebotomus chinensis, the primary vector of visceral leishmaniasis in China: insights from chromosome-level assembly and comparative analysis

Infectious Diseases of Poverty
Background Phlebotomus chinensis is the primary vector of visceral leishmaniasis (VL) in China. However, the lack of a high-quality genome assembly for this species has limited research on its biology, vector-pathogen interactions, and evolutionary ...
Haowei Dong, Wenqi Shan, Qiuming Zhou, Hao Yuan, Kang Wang, Yuanyuan Li, Wenbing Zhong, Maimaitijiang Wumaier, Anjie Yang, Huiying Chen, Bing Rui, Yajun Ma, Shizhu Li, Heng Peng   +13 more
doaj   +1 more source

Current perspectives on circadian regulation of mitochondrial dynamics in mood disorders and perioperative stress

Frontiers in Pharmacology
Mitochondria act as a central integrative hub for oxidative phosphorylation, calcium homeostasis and metabolic signaling, reflecting their evolutionary origin from an α-proteobacterial endosymbiont.
Florencia Verbal, Florencia Verbal, Nicole Rubilar, Nicole Rubilar, Ana M Marileo, Humberto Fierro, Oscar Guillermo Ramirez-Molina, Araceli Pinto-Leon, Gonzalo E Yevénes, Jorge Fuentealba, Jorge Fuentealba, Jessica Panes-Fernández, Jessica Panes-Fernández   +12 more
doaj   +1 more source

The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry Diagonal

Zoologica Scripta, EarlyView.
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi, Vinícius A. São Pedro, Felipe Magalhães, Marcelo Gehara, Eliana F. Oliveira, Gabriel C. Costa, Frank T. Burbrink, Edward A. Myers, Guarino R. Colli, Miguel T. Rodrigues, Adrian A. Garda   +10 more
wiley   +1 more source

Mitochondrial genome of the North American Morus rubra L. (red mulberry) reveals plastome gene transfer and essence of RNA editing

Discover Plants
Morus rubra L. (Family: Moraceae), native to eastern North America, is distributed in the heart of pristine riparian forests and holds important ethnobotanical and ecological values.
Bibek Adhikari, Emily Ringgenberg, Gavin Smith, Ryan Johnson, Sanam Parajuli, Jeffrey D. Carstens, Madhav P. Nepal   +6 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Hot alkaline lysis gDNA extraction from formalin-fixed archival tissues [PDF]

Formalin fixation of natural history specimens and histopathological material has historically been viewed as an impediment to successful genomic analysis.
Alexander, Marina, Grewe, Peter M., Hahn, Erin E., Holleley, Clare E., Stiller, Jiri   +4 more
core   +1 more source