Results 31 to 40 of about 1,397 (158)

Papel da mitocôndria na citoxicidade induzida pela abamectina em hepatócitos isolados de rato [PDF]

, 2012
Abamectina (ABA), pertencente à família das avermectinas é utilizada mundialmente como parasiticida, porém a intoxicação por ABA pode prejudicar o funcionamento hepático.
Maioli, Marcos Antonio
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Estudos in vitro usando um sistema de transporte de DNA plasmídico (pDNA) com afinidade pela mitocôndria [PDF]

, 2018
A mitocôndria é um organelo celular que possui o seu próprio genoma, o ADN mitocondrial (ADNmt). Apesar de bastante pequeno quando comparado com o ADN nuclear (ADNn), mutações ao nível do ADNmt são bastante frequentes devido à falta de mecanismos de ...
Melo, Ana Cristina Candeias
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The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, Volume 600, Issue 12, Page 1770-1781, June 2026.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Fracionamento da mitocôndria [PDF]

Apresenta a metodologia de fracionamento dos componentes da mitocôndria por centrifugaçãoComponente Curricular::Educação Superior::Ciências Biológicas::Biologia ...
Fundação Centro de Ciências e Educação Superior a Distância do Estado do Rio de Janeiro (CECIERJ)
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Mitochondrial ultrastructural and atpase changes during the life cycle of Ascaris Suum

Memorias do Instituto Oswaldo Cruz, 1982
Ultrastructural morphology and ATPase specific activities of mitochondria isolated from 1-celled fertilized egg, 10-day embryo, 21-day infective larvae and adult body wall muscle of Ascaris suum and rat liver were determined and compared.
G. E. Rodrick, S. D. Long, W. A. Sodeman Junior, D. L. Smith   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Optimization and sensitivity analysis of fast ethanol assay in maize seeds

Journal of Seed Science
: The evaluation of seed deterioration is very important to control the quality of the seeds stored. This study aimed to investigate the potential of fast ethanol assay for seed quality assessment of maize stored under different conditions.
Damrongvudhi Onwimol, Thunyapuk Rongsangchaicharean, Pitipong Thobunluepop, Tanapon Chaisan, Wanchai Chanprasert   +4 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, Volume 16, Issue 6, Page 1087-1101, June 2026.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Ensinando ciência com arte: A Mitocôndria em 3 Atos, O Ciclo de Krebs, A Explosão do Saber [PDF]

, 2002
FAPERJCAPESVITAEApresentação de três vídeos educativos para estudantes e professores de Nível Médio, Superior e Pós Graduação na área biomédica. O primeiro vídeo descreve a estrutura e funcionamento da mitocôndria, o segundo descreve o Ciclo de Krebs ...
Meis, Leopoldo de
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