Results 41 to 50 of about 1,397 (158)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, Volume 16, Issue 6, Page 1115-1131, June 2026.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Pérdida secundaria de la fotosíntesis: el caso de las algas incoloras y de algunos parásitos

Botan‪ical Sciences, 2017
Esta  revisión  pretende ilustrar un  fenómeno muy  interesante e n la  naturaleza: la perdida secundaria de  la fotosíntesis y sus efectos en los genomas del cloroplasto y de la mitocondria. Se describe cómo los genomas de los plástidos incoloros se han
Emma Berta Gutiérrez-Cirios-Madrid
doaj   +1 more source

Desenvolvimento de um vetor com afinidade pela mitocôndria [PDF]

, 2015
Para além dos 23 pares de cromossomas que uma célula contem, o genoma humano também é constituído pelo genoma mitocondrial. A principal função da mitocôndria é a produção de níveis altos de energia (ATP) usada pelas células por via da respiração aeróbia.
Costa, Carolina Vicente Santos
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, Volume 16, Issue 6, Page 1213-1221, June 2026.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Ultrastructural features of Mimulus aurantiacus (Scrophulariaceae) pollen tubes in vivo

Anais da Academia Brasileira de Ciências, 2009
The aim of this study is to give information on ultrastructure of in vivo pollen tubes of Mimulus aurantiacus which were collected from the Botanical Garden of the University of California at Berkeley.
Nuran Ekici, Feruzan Dane, Göksel Olgun
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Biogenêse mitocondrial e exercício físico: hipótese do acoplamento elétrico-transcripcional

Revista Brasileira de Educação Física e Esporte : RBEFE, 2015
Resumo Uma das principais modificações ocorridas no organismo em decorrência do treinamento físico-esportivo envolvendo exercícios físicos de longa duração é o aumento na quantidade e qualidade funcional de mitocôndrias do tecido muscular esquelético ...
Benedito PEREIRA
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, Volume 16, Issue 6, Page 1166-1180, June 2026.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

COM v3.1: Consumo de oxigênio por mitocôndria [PDF]

, 2016
Esse software permite simular experimentos para verificar a influência de alguns compostos (substratos, inibidores e desacopladores) sobre a velocidade de consumo de oxigênio pelas mitocôndrias.
Galembeck, Eduardo, Kimura, Eduardo Kenji, Kubo, Ricardo T., Torres, Bayardo Baptista, Macedo, Denise Vaz de, Brum, Itaraju Junior Baracuhy   +5 more
core   +2 more sources

Papel del péptido mitocondrial humanina como blanco terapéutico en cáncer y neurodegeneración

NOVA, 2019
La humanina es un péptido derivado de la mitocondria con efectos protectores robustos contra una gran variedad de estímulos citotóxicos en diversos tipos celulares.
Antonela Sofía Asad, Camila Florencia Zuccato, Alejandro Javier Nicola Candia, María Florencia Gottardo, Mariela Alejandra Moreno Ayala, María Susana Theas, Adriana Seilicovich, Marianela Candolfi   +7 more
doaj   +1 more source