Results 31 to 40 of about 2,143,132 (361)

Lipid-droplet associated mitochondria promote fatty-acid oxidation through a distinct bioenergetic pattern in male Wistar rats

open access: yesNature Communications, 2023
Mitochondria empower the liver to regulate lipid homeostasis by enabling fatty acid oxidation during starvation and lipogenesis during nutrient-rich conditions.
Noble Kumar Talari   +6 more
semanticscholar   +1 more source

ABCC6 is a basolateral plasma membrane protein [PDF]

open access: yes, 2013
RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A.   +11 more
core   +4 more sources

Contribution of mitochondria to injury of hepatocytes and liver tissue by hyperthermia

open access: yesMedicina, 2017
Objective: The aim of this study was to investigate functional changes of liver mitochondria within the experimentally modeled transition zone of radiofrequency ablation and to estimate possible contribution of these changes to the energy status of liver
Rasa Žūkienė   +6 more
doaj   +1 more source

Detailed mitochondrial phenotyping by high resolution metabolomics. [PDF]

open access: yesPLoS ONE, 2012
Mitochondrial phenotype is complex and difficult to define at the level of individual cell types. Newer metabolic profiling methods provide information on dozens of metabolic pathways from a relatively small sample.
James R Roede   +4 more
doaj   +1 more source

Nucleic acids and protein synthesis in cancer cell mitochondria. I. Nucleic acids in rat hepatoma mitochondria [PDF]

open access: yes, 1967
The contents of nucleic acids in rat liver and hepatoma mitochondria and the physico-chemical properties on DNA's isolated from these mitochondria were comparatively investigated. The results are briefly summarized as follows. 1.
Inaba, Kozo
core   +1 more source

Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria

open access: yesRedox Biology, 2018
Mitochondria are critical sources of hydrogen peroxide (H2O2), an important secondary messenger in mammalian cells. Recent work has shown that O2•-/H2O2 emission from individual sites of production in mitochondria is regulated by protein S ...
Julia Chalker   +3 more
doaj   +1 more source

The Apoptosis of Liver Cancer Cells Promoted by Curcumin/TPP-CZL Nanomicelles With Mitochondrial Targeting Function

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
The mitochondrion is one of the most important cellular organelles, and many drugs work by acting on mitochondria. Curcumin (Cur)-induced apoptosis of HepG2 in liver cancer cells is closely related to the function of inhibiting mitochondria. However, the
Wanyu Li   +7 more
doaj   +1 more source

Potassium Metabolism of Liver Mitochondria.

open access: yesExperimental Biology and Medicine, 1953
SummaryRabbit liver mitochondria contain K which cannot be removed by repeated washings with NaCl solutions at 2°C. This K fraction exchanges with ambient K under appropriate metabolic conditions, indicating a dependence of K metabolism on aerobic oxidation. Orthophosphate depresses the mitochondrial K level.
S W, STANBURY, G H, MUDGE
openaire   +2 more sources

Studies on the organellae of liver of cancer bearing animals II. Catalase activity in the liver of animals treated with cyto-plasmic organellae from hepatoma cell (AH 130) and liver cell of the hepatoma bearing animals [PDF]

open access: yes, 1961
The author studied the distribution of polysaccharides and the amino-acid composition of cytoplasmic organellae, the problems that have come to call a great interest in the field of studies on cancer bearing animals.
Kimoto, Tetsuo
core   +1 more source

Fatty liver and insulin resistance in obese Zucker rats: No role for mitochondrial dysfunction [PDF]

open access: yes, 2008
The relationship between insulin resistance and mitochondrial function is of increasing interest. Studies looking for such interactions are usually made in muscle and only a few studies have been done in liver, which is known to be a crucial partner in ...
G. Simard   +6 more
core   +4 more sources

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