Results 151 to 160 of about 156,228 (267)

Exercise training does not mitigate high-phosphate diet-induced mitochondrial dysfunction in skeletal muscle in male mice. [PDF]

Physiol Rep
Sanders HF, Kolonay DW, Blackwell JA, Liu J, Dobrski IR, Branch DA, Lefers LA, Kern BH, Baskin KK.   +8 more
europepmc   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Impaired Exercise-Induced Mitophagy in Aged Muscle Coincides With Altered mitoAMPKα in Male Mice. [PDF]

Aging Cell
Amiri N, Nichenko AS, Churchill A, Willoughby OS, Pettit TD, Najt CP, Rodriguez-Mias RA, Villen J, Drake JC.   +8 more
europepmc   +1 more source

Cis‐eQTL‐Driven Allele‐Specific Expression Contributes to Feed Efficiency Heterosis in Broilers

Animal Research and One Health, EarlyView.
This study analyzed cecal mucosa transcriptomes of broiler purebred and hybrid populations, identified key candidate genes associated with feed efficiency heterosis, and elucidated how cis‐eQTL–driven allele‐specific expression contributes to non‐additive gene expression and hybrid performance in broilers.
Zehao Li, Qiang Huang, Shuang Gu, Yiyuan Yan, Guangqi Li, Guiqin Wu, Congjiao Sun, Ning Yang, Junying Li, Chaoliang Wen   +9 more
wiley   +1 more source

Skeletal Muscle Fibre Type Determines Mitochondrial and Metabolic Responses to Hypoxia and Pulmonary Inflammation in Young Adult Rats. [PDF]

J Cachexia Sarcopenia Muscle
Gavrielatos A, Cottet-Rousselle C, Brocker N, Tellier C, Achouri A, Prola A, Dubouchaud H, Chabert C.   +7 more
europepmc   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Inhibition of the AMPK/PGC-1α/Mfn2 Axis is Associated with Mitochondria-Endoplasmic Reticulum Dysfunction and Ultrastructural Remodeling in a Rat Model of Myofascial Trigger Points [Letter]. [PDF]

J Pain Res
Wang B, Wu S, Liu Z, Lv L, Lv Z.
europepmc   +1 more source

Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: The Study of Muscle, Mobility and Aging

Arthritis &Rheumatology, EarlyView.
Objective The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing in vastus lateralis muscle, resulting in 523 participants (56% female).
Daniel S. Evans, Tyler A. Mansfield, Gina M. Many, Tyler J. Sagendorf, Samaneh Farsijani, Bret H. Goodpaster, Lauren M. Sparks, Nancy E. Lane   +7 more
wiley   +1 more source

Targeting ubiquitin-dependent mitochondrial autophagy and apoptosis in sarcopenia: the therapeutic potential of phytochemicals. [PDF]

Discov Nano
Zeng Y, Wang P.
europepmc   +1 more source

MDL‐800–Induced Sirtuin 6 Activation Decreases Age‐Associated Osteoarthritis in Mice

Arthritis &Rheumatology, EarlyView.
Objective Sirtuin 6 (SIRT6) is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of MDL‐800, a small molecule activator of SIRT6, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez, Pranay Ramteke, Bahiyah Watson, Owen Haslam, Eirene Choi, Susan Chubinskaya, Mandy J. Peffers, William R. Davis, Jacqueline Shine, Brian O. Diekman, Richard F. Loeser, Theresa A. Freeman, Makarand V. Risbud, John A. Collins   +13 more
wiley   +1 more source