Results 241 to 250 of about 1,131,582 (303)

Angiogenin mediates cell-cell fusion as a mitochondrial RNA processing enzyme. [PDF]

Bone Res
Shen K, Zeng Y, Wang J, Song K, Kumar S, Gao P, Hu GF, Cao X, Wan M.   +8 more
europepmc   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

β-Hydroxybutyrate-induced mitochondrial dysfunction and oxidative stress in BMSCs are ameliorated by mitophagy activation. [PDF]

Front Cell Dev Biol
Tang T, Zhou J, Jia X, Shao J, Wang M, Xia S, Chen S, Sun W, Wang J, Lai S.   +9 more
europepmc   +1 more source

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

Medicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang, Wen‐Bi He, Fei‐Peng Chen, Jiong‐Xing Huang, Lin Zhu, Xiao‐Guang Liu   +5 more
wiley   +1 more source

UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice. [PDF]

J Clin Invest
Zhang B, He Y, Su T, Li X, Zhang X, Liu R, Han X, Zhang R, Yang C, Liu X, Hou Q, Zhang Z, Xie Y, Liu G, Yang X.   +14 more
europepmc   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

The pseudokinase domain PK1 of UNC-89/obscurin is required for mitochondrial morphology and function in C. elegans. [PDF]

J Muscle Res Cell Motil
Matsunaga Y, Ghazal N, Heim A, Dorendorf T, Qadota H, Wang Y, Mayer TU, Mayans O, Kwong JQ, Benian GM.   +9 more
europepmc   +1 more source

Mitochondrial Quality Control in Age-Related Diseases: From Molecular Architecture to Precision Therapeutics. [PDF]

Antioxidants (Basel)
Che J, Sun Y, Wang F, Feng Q, Xu C, Li X.   +5 more
europepmc   +1 more source

Mechanistic pathways linking gut microbial metabolites, microbial structural products, and host-microbe co-metabolites to mitochondrial function. [PDF]

Gut Microbes
Frye RE, Rossignol DA.
europepmc   +1 more source

ALS: An Organism-Wide Bioenergetic Failure Due to Mitochondrial Dysfunctions? [PDF]

Biomolecules
Mitsumoto H, Blasco H, Corcia P, Silani V.   +3 more
europepmc   +1 more source