Results 11 to 20 of about 1,007,169 (424)

Mitochondria and apoptosis. [PDF]

open access: yesEuropean Journal of Biochemistry, 1998
A variety of key events in apoptosis focus on mitochondria, including the release of caspase activators (such as cytochrome c), changes in electron transport, loss of mitochondrial transmembrane potential, altered cellular oxidation-reduction, and ...
D. Green, John Calvin Reed
semanticscholar   +6 more sources

Mitochondria and Cancer [PDF]

open access: yesMolecular Cell, 2016
Decades ago, Otto Warburg observed that cancers ferment glucose in the presence of oxygen, suggesting that defects in mitochondrial respiration may be the underlying cause of cancer. We now know that the genetic events that drive aberrant cancer cell proliferation also alter biochemical metabolism, including promoting aerobic glycolysis, but do not ...
Sejal Vyas, Elma Zaganjor, M. Haigis
semanticscholar   +4 more sources

MITOCHONDRIA OF PROTOZOA [PDF]

open access: bronzeThe Journal of Cell Biology, 1956
A study of thin sections of Paramecium multimicronucleatum, Tetrahymena pyriformis, Tokophrya infusionum, and Amoeba proteus shows that the mitochondria in all these protozoa are similar in certain aspects of their fine structure to that described in metazoan cells.
Albert W. Sedar, Maria A. Rudzinska
openalex   +4 more sources

Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

open access: yesChemical Reviews, 2017
Mitochondria are recognized as one of the most important targets for new drug design in cancer, cardiovascular, and neurological diseases. Currently, the most effective way to deliver drugs specifically to mitochondria is by covalent linking a lipophilic
Jacek Zielonka   +2 more
exaly   +2 more sources

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

open access: yesNature, 2018
Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and dysfunction of both organelles has been observed in multiple diseases.
Yvette C Wong   +2 more
exaly   +2 more sources

Mitochondria in Poliomyelitis [PDF]

open access: greenThe Journal of Nervous and Mental Disease, 1918
n ...
Gertrude Fisher McCann
openalex   +4 more sources

Blood contains circulating cell‐free respiratory competent mitochondria

open access: yesFASEB Journal, 2020
Mitochondria are considered as the power‐generating units of the cell due to their key role in energy metabolism and cell signaling. However, mitochondrial components could be found in the extracellular space, as fragments or encapsulated in vesicles. In
Brice Pastor   +2 more
exaly   +2 more sources

Sirt1 and the Mitochondria

open access: yesMolecules and Cells, 2016
Sirt1 is the most prominent and extensively studied member of sirtuins, the family of mammalian class III histone deacetylases heavily implicated in health span and longevity.
B. Tang
semanticscholar   +5 more sources

Hot mitochondria? [PDF]

open access: yesPLoS Biology, 2018
Mitochondria generate most of the heat in endotherms. Given some impedance of heat transfer across protein-rich bioenergetic membranes, mitochondria must operate at a higher temperature than body temperature in mammals and birds.
Nick Lane
doaj   +5 more sources

Green Extraction of Phenolic Compounds from Lotus (Nelumbo nucifera Gaertn) Leaf Using Deep Eutectic Solvents: Process Optimization and Antioxidant Activity

open access: yesSeparations, 2023
Natural deep eutectic solvents (NDESs) were used to extract flavonoids and polyphenols from lotus (Nelumbo nucifera Gaertn.) leaves at the same time, and the extraction process was optimized to provide reference for the effective development and ...
Jiwei Yang   +10 more
doaj   +1 more source

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