Results 11 to 20 of about 690,904 (305)

Calcium-binding properties, stability, and osteogenic ability of phosphorylated soy peptide-calcium chelate

open access: yesFrontiers in Nutrition, 2023
IntroductionBioactive peptides based on foodstuffs are of particular interest as carriers for calcium delivery due to their safety and high activity. The phosphorylated peptide has been shown to enhance calcium absorption and bone formation.MethodA novel
Xiao Kong   +12 more
doaj   +1 more source

A Perspective on Accelerated Aging Caused by the Genetic Deficiency of the Metabolic Protein, OPA1

open access: yesFrontiers in Neurology, 2021
Autosomal Dominant Optic Atrophy (ADOA) is an ophthalmological condition associated primarily with mutations in the OPA1 gene. It has variable onset, sometimes juvenile, but in other patients, the disease does not manifest until adult middle age despite ...
Irina Erchova   +3 more
doaj   +1 more source

Mitochondria and cell death-associated inflammation

open access: yesCell Death and Differentiation, 2022
Mitochondria have recently emerged as key drivers of inflammation associated with cell death. Many of the pro-inflammatory pathways activated during cell death occur upon mitochondrial outer membrane permeabilization (MOMP), the pivotal commitment point ...
Esmee Vringer, S. Tait
semanticscholar   +1 more source

Expressions of mitochondria-related genes in pregnant women with subclinical hypothyroidism, and expressions of miRNAs in maternal and cord blood

open access: yesThyroid Research, 2023
Background Subclinical hypothyroidism in pregnancy and definition by upper thyrotropin (TSH) cutoff are controversial. As mitochondria are influenced by thyroid hormones, the purpose in this study was to measure expression of mitochondria-related genes ...
Julie Kristine Guldberg Stryhn   +3 more
doaj   +1 more source

Potential Therapeutic Functions of PU-91 and Quercetin in Personalized Cybrids Derived from Patients with Age-Related Macular Degeneration, Keratoconus, and Glaucoma

open access: yesAntioxidants, 2023
The aim of this study is to investigate the therapeutic potential of higher doses of PU-91, quercetin, or in combination on transmitochondrial cybrid cell lines with various mtDNA haplogroups derived from patients with age-related macular degeneration ...
Nasim Salimiaghdam   +8 more
doaj   +1 more source

Sarcopenia and peripheral arterial disease: a systematic review

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2020
Background Patients with lower extremity peripheral arterial disease (PAD) and sarcopenia are a population at risk requiring specific and targeted care.
Mégane Pizzimenti   +6 more
doaj   +1 more source

How mitochondria produce reactive oxygen species

open access: yesBiochemical Journal, 2008
The production of ROS (reactive oxygen species) by mammalian mitochondria is important because it underlies oxidative damage in many pathologies and contributes to retrograde redox signalling from the organelle to the cytosol and nucleus. Superoxide (O2•−
M. Murphy
semanticscholar   +1 more source

Assessing the effects of mitofusin 2 deficiency in the adult heart using 3D electron tomography [PDF]

open access: yes, 2017
The effects of mitofusin 2 (MFN2) deficiency, on mitochondrial morphology and the mitochondria-junctional sarcoplasmic reticulum (jSR) complex in the adult heart, have been previously investigated using 2D electron microscopy, an approach which is unable
Cabrera-Fuentes, Hector   +12 more
core   +2 more sources

Isolation and analysis of fractions enriched in WrappER-associated mitochondria from mouse liver

open access: yesSTAR Protocols, 2021
Summary: The endoplasmic reticulum (ER) plays a central role in lipid homeostasis, but the role of individual ER subdomains in lipid biology has not been elucidated.
Nicolò Ilacqua   +2 more
doaj   +1 more source

Depletion of mitochondria in mammalian cells through enforced mitophagy [PDF]

open access: yes, 2016
Mitochondria are not only the 'powerhouse' of the cell; they are also involved in a multitude of processes that include calcium storage, the cell cycle and cell death.
Correia-Melo, Clara   +3 more
core   +1 more source

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