Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung +5 more
wiley +1 more source
Downregulation of microRNA-494 drives mitochondrial biogenesis and function in trained muscle. [PDF]
Pálešová N +10 more
europepmc +1 more source
Reclaiming Anatomy as Method: From Morphological Reasoning to Clinical Relevance
ABSTRACT In recent decades, molecular biology and omics technologies have profoundly reshaped biomedical research, with genomics, proteomics, and other high‐throughput approaches dominating scientific agendas and funding priorities. Within this molecular paradigm, however, the anatomical sciences face an epistemic and institutional tension: morphology,
Katia Cortese, Marco Frascio
wiley +1 more source
Engineered Tan-CDs@AS-IV Nanosystem Orchestrates Mitochondrial Biogenesis and Intercellular Transfer to Restore Endothelial Function via PGC-1α and Cx43 Signaling Pathways. [PDF]
Wang H, Wang X, Liu S, Liu C.
europepmc +1 more source
Comparative Study of Free and Total Fatty Acids of Spreadable Cheeses by Mass Spectrometry Methods
This study focuses on the determination of FFAs in spreadable cheeses and alternatives using a fast Liquid Chromatography‐High Resolution Mass Spectrometry method. A Gas Chromatography‐Mass Spectrometry method was used to determine the composition (%) of total FAs in the same samples.
Christiana Mantzourani +6 more
wiley +1 more source
Exercise training induces mitochondrial biogenesis, while high-fat diet increases the ability of mitochondria to use long and short-chain fatty acids. [PDF]
Dowling JL +5 more
europepmc +1 more source
Biogenesis of mitochondrial membrane proteins
Teintze, Martin +4 more
openaire +3 more sources
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr +7 more
wiley +1 more source
Human milk-derived 5'-UMP promotes thermogenesis and mitochondrial biogenesis to ameliorate obesity. [PDF]
Zhang L +8 more
europepmc +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source

