Results 1 to 10 of about 112,477 (144)

Insights into lysosome-related organelle biogenesis: melanosome as a model organelle [PDF]

open access: yesFrontiers in Cell and Developmental Biology
Lysosome-related organelles (LROs) encompass specialized intracellular compartments that share features with lysosomes while fulfilling distinct physiological roles, with melanosomes representing the best-studied example.
Duarte C. Barral   +6 more
doaj   +4 more sources

Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance [PDF]

open access: yeseLife, 2014
Fluctuations in organelle abundance can profoundly limit the precision of cell biological processes from secretion to metabolism. We modeled the dynamics of organelle biogenesis and predicted that organelle abundance fluctuations depend strongly on the ...
Shankar Mukherji, Erin K O'Shea
doaj   +6 more sources

Expanding magnetic organelle biogenesis in the domain Bacteria [PDF]

open access: yesMicrobiome, 2020
Background The discovery of membrane-enclosed, metabolically functional organelles in Bacteria has transformed our understanding of the subcellular complexity of prokaryotic cells.
Wei Lin   +8 more
doaj   +7 more sources

Membrane dynamics and organelle biogenesis—lipid pipelines and vesicular carriers [PDF]

open access: yesBMC Biology, 2017
Discoveries spanning several decades have pointed to vital membrane lipid trafficking pathways involving both vesicular and non-vesicular carriers.
Christopher J. Stefan   +19 more
doaj   +2 more sources

Organelle biogenesis and autophagy [PDF]

open access: yesMol Biol Cell, 2012
Is mitochondrial volume maintained during polarized cell growth? How well do cells ensure that they maintain uniform organelle distribution when they undergo polarized cell growth and subsequent division. S. Rafelski from the Marshall laboratory at University of California–San Francisco used three-dimensional, computationalmodeling methods to ...
Simonsen A, Voeltz G.
europepmc   +2 more sources

Asgard Arf GTPases can act as membrane-associating molecular switches with the potential to function in organelle biogenesis [PDF]

open access: yesNature Communications
Inward membrane budding, i.e., the bending of membrane towards the cytosol, is essential for forming and maintaining eukaryotic organelles. In eukaryotes, Arf GTPases initiate this inward budding.
Jing Zhu   +17 more
doaj   +2 more sources

Biogenesis of a Bacterial Organelle: The Carboxysome Assembly Pathway [PDF]

open access: yesCell, 2013
The carboxysome is a protein-based organelle for carbon fixation in cyanobacteria, keystone organisms in the global carbon cycle. It is composed of thousands of subunits including hexameric and pentameric proteins that form a shell to encapsulate the enzymes ribulose 1,5-bisphosphate carboxylase/oxygenase and carbonic anhydrase.
Jeffrey Cameron   +2 more
exaly   +3 more sources

Cell-to-cell variability in organelle abundance reveals mechanisms of organelle biogenesis [PDF]

open access: yesPhysical Review E, 2019
30 pages, 3 Figures and 1 Table.
Sandeep Choubey   +2 more
exaly   +5 more sources

Self-propagating organelle biogenesis on synthetic beads

open access: yes
Abstract Centrosomes are complex organelles that comprise multiple copies of hundreds of different proteins, yet they can precisely duplicate every cell cycle. Here we reconstitute centrosome duplication on synthetic beads programmed to recruit core centrosome assembly proteins when injected into ...
Peng M   +13 more
europepmc   +2 more sources

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