Results 11 to 20 of about 196,311 (276)
Effects of bursty synthesis in organelle biogenesis [PDF]
Mathematical BiosciencesA fundamental question of cell biology is how cells control the number of organelles. The processes of organelle biogenesis, namely de novo synthesis, fission, fusion, and decay, are inherently stochastic, producing cell-to-cell variability in organelle abundance. In addition, experiments suggest that the synthesis of some organelles can be bursty.
Dipjyoti Das
exaly +6 more sources
Inheritance and biogenesis of organelles in the secretory pathway
Nature Reviews Molecular Cell Biology, 2007 In eukaryotic cells, cellular functions are compartmentalized into membrane-bound organelles. This has many advantages, as shown by the success of the eukaryotic lineage, but creates many problems for cells, such as the need to build and partition these organelles during cell growth and division.
Francis A. Barr
exaly +6 more sources
Organelle biogenesis and interorganellar connections: Better in contact than in isolation. [PDF]
Commun Integr Biol, 2014 Membrane contact sites (MCSs) allow the exchange of molecules and information between organelles, even when their membranes cannot fuse directly. In recent years, a number of functions have been attributed to these contacts, highlighting their critical role in cell homeostasis.
Daniele T, Schiaffino MV.
europepmc +3 more sources
Autophagy protein Atg7 is essential for maintaining malaria parasite cellular homeostasis and organelle biogenesis [PDF]
mBioPlasmodium parasites have a complex life cycle that transitions between mosquito and mammalian hosts, and undergo continuous cellular remodeling to adapt to various drastic environments.
Akancha Mishra +4 more
doaj +2 more sources
A coordinated transcriptional program controls de novo Golgi biogenesis [PDF]
The EMBO JournalThe Golgi apparatus expands during differentiation and increased secretory demand, yet the transcriptional mechanisms governing its biogenesis remain poorly defined.
Francesca Forno +18 more
doaj +2 more sources
Biogenesis of the trypanosome endo-exocytotic organelle is cytoskeleton mediated.
PLoS Biology, 2008 Trypanosoma brucei is a protozoan parasite that is used as a model organism to study such biological phenomena as gene expression, protein trafficking, and cytoskeletal biogenesis. In T.
Mélanie Bonhivers +3 more
doaj +2 more sources
Correction: Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance
eLife, 2015 Shankar Mukherji, Erin K O'Shea
doaj +2 more sources
Regulation of Organelle Biogenesis [PDF]
Cell, 1996 We are grateful to the members of the Walter laboratory and of the many other laboratories whose work is reviewed for their helpful discussions, for their critical reading of this manuscript, and for making preprints available prior to publication. Because of space limitations, we were not able to include many of the primary references, and the readers
Nunnari, Jodi, Walter, Peter
openaire +2 more sources
Organelle biogenesis: en BLOC exchange for RAB32 and RAB38. [PDF]
Curr Biol, 2012 SummaryProminent subtypes of the genetic disorder Hermansky–Pudlak syndrome result from defects in a mysterious protein complex, BLOC-3. New work identifies BLOC-3 as a guanine nucleotide exchange factor for two RAB GTPases previously implicated in ...
Marks MS.
europepmc +2 more sources
The Biogenesis of Lysosomes and Lysosome-Related Organelles [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 Lysosomes were once considered the end point of endocytosis, simply used for macromolecule degradation. They are now recognized to be dynamic organelles, able to fuse with a variety of targets and to be re-formed after fusion events. They are also now known to be the site of nutrient sensing and signaling to the cell nucleus. In addition, lysosomes are
J Paul, Luzio +3 more
openaire +2 more sources