Results 11 to 20 of about 108,308 (280)

Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance. [PDF]

open access: yesElife, 2014
Fluctuations in organelle abundance can profoundly limit the precision of cell biological processes from secretion to metabolism. We modeled the dynamics of organelle biogenesis and predicted that organelle abundance fluctuations depend strongly on the ...
Mukherji S, O'Shea EK.
europepmc   +8 more sources

Expanding magnetic organelle biogenesis in the domain Bacteria. [PDF]

open access: yesMicrobiome, 2020
Background: The discovery of membrane-enclosed, metabolically functional organelles in Bacteria has transformed our understanding of the subcellular complexity of prokaryotic cells.
Lin W   +8 more
europepmc   +9 more sources

Membrane fusion in organelle biogenesis

open access: yesCurrent Opinion in Cell Biology, 1996
International audienceIntracellular membrane fusion is a fascinating reaction that is crucial for cellular function. Several components of the membrane fusion machinery have been identified, although a precise understanding of the fusion mechanism is ...
Malhotra, Vivek   +3 more
core   +5 more sources

Biogenesis of the trypanosome endo-exocytotic organelle is cytoskeleton mediated.

open access: yesPLoS Biology, 2008
Trypanosoma brucei is a protozoan parasite that is used as a model organism to study such biological phenomena as gene expression, protein trafficking, and cytoskeletal biogenesis. In T.
Derrick R Robinson   +8 more
core   +2 more sources

Cytosolic Quality Control of Mitochondrial Protein Precursors-The Early Stages of the Organelle Biogenesis. [PDF]

open access: yesInt J Mol Sci, 2021
With few exceptions, proteins that constitute the proteome of mitochondria originate outside of this organelle in precursor forms. Such protein precursors follow dedicated transportation paths to reach specific parts of mitochondria, where they complete ...
Lenkiewicz AM   +2 more
europepmc   +2 more sources

Organelle biogenesis: en BLOC exchange for RAB32 and RAB38. [PDF]

open access: yesCurr Biol, 2012
SummaryProminent subtypes of the genetic disorder Hermansky–Pudlak syndrome result from defects in a mysterious protein complex, BLOC-3. New work identifies BLOC-3 as a guanine nucleotide exchange factor for two RAB GTPases previously implicated in ...
Marks MS.
europepmc   +2 more sources

Regulation of Organelle Biogenesis [PDF]

open access: yesCell, 1996
We are grateful to the members of the Walter laboratory and of the many other laboratories whose work is reviewed for their helpful discussions, for their critical reading of this manuscript, and for making preprints available prior to publication. Because of space limitations, we were not able to include many of the primary references, and the readers
Nunnari, Jodi, Walter, Peter
openaire   +2 more sources

The Biogenesis of Lysosomes and Lysosome-Related Organelles [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2014
Lysosomes were once considered the end point of endocytosis, simply used for macromolecule degradation. They are now recognized to be dynamic organelles, able to fuse with a variety of targets and to be re-formed after fusion events. They are also now known to be the site of nutrient sensing and signaling to the cell nucleus. In addition, lysosomes are
J Paul, Luzio   +3 more
openaire   +2 more sources

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