Results 41 to 50 of about 196,311 (276)

Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B [PDF]

, 2010
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa.
Langsley, G, Bernardo J. Foth, Ferguson, D.J. P., Ferguson, DJ, Markus Meissner, David J. P. Ferguson, Foth, B.J., Carolina Agop-Nersesian, Langsley, G., Agop-Nersesian, C, Meissner, M, Saskia Egarter, Meissner, M., Egarter, S., Sibley, L.D., Egarter, S, Bernardo J Foth, Gordon Langsley, Agop-Nersesian, C., David J P Ferguson, Foth, BJ   +20 more
core   +1 more source

ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites

mBio, 2018
Plasmodium parasites and related pathogens contain an essential nonphotosynthetic plastid organelle, the apicoplast, derived from secondary endosymbiosis.
Marta Walczak, Suresh M. Ganesan, Jacquin C. Niles, Ellen Yeh   +3 more
doaj   +1 more source

TFAP2 transcription factors are regulators of lipid droplet biogenesis

eLife, 2018
How trafficking pathways and organelle abundance adapt in response to metabolic and physiological changes is still mysterious, although a few transcriptional regulators of organellar biogenesis have been identified in recent years.
Cameron C Scott, Stefania Vossio, Jacques Rougemont, Jean Gruenberg   +3 more
doaj   +1 more source

Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells

iScience, 2022
Summary: PIWI-interacting RNAs (piRNAs) bind to PIWI proteins to assemble the piRISC, which represses germline transposons. Maelstrom (Mael) is necessary for piRISC biogenesis in germ cells, but its function remains unclear.
Yurika Namba, Yuka W. Iwasaki, Kazumichi M. Nishida, Hidenori Nishihara, Tetsutaro Sumiyoshi, Mikiko C. Siomi   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Melanosomes: Biogenesis, Properties, and Evolution of an Ancient Organelle [PDF]

Physiological Reviews, 2019
Melanosomes are organelles that produce and store melanin, a widespread biological pigment with a unique suite of properties including high refractive index, semiconducting capabilities, material stiffness, and high fossilization potential. They are involved in numerous critical biological functions in organisms across the tree of life.
Liliana D’Alba, Matthew D. Shawkey
openaire   +2 more sources

Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement [PDF]

, 2010
Compartmentalization is an important process, since it allows the segregation of metabolic activities and, in the era of synthetic biology, represents an important tool by which defined microenvironments can be created for specific metabolic functions ...
Prentice, M.B., Mulvihill, D.P., Frank, S., Bhella, D., Frank, Stefanie, Parsons, J.B., Bhella, David, Prentice, Michael B., Liang, M., Mulvihill, Daniel P., Warren, Martin J., Parsons, Joshua B., Warren, M.J., Liang, Mingzhi   +13 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Reciprocal regulation of protein synthesis and carbon metabolism for thylakoid membrane biogenesis [PDF]

, 2013
Metabolic control of gene expression coordinates the levels of specific gene products to meet cellular demand for their activities. This control can be exerted by metabolites acting as regulatory signals and/or a class of metabolic enzymes with dual ...
Bohne, Alexandra-Viola, Marco Schottkowski, Michael Lidschreiber, Zerges, William, Markus Piotrowski (169373), Markus Piotrowski, Michael Lidschreiber (138963), Christian Schwarz, Alexandra-Viola Bohne (281295), Marco Schottkowski (281297), William Zerges, Nickelsen, Jörg, Jörg Nickelsen (13576), Piotrowski, Markus, Alexandra-Viola Bohne, Christian Schwarz (281296), Lidschreiber, Michael, Jörg Nickelsen, Schottkowski, Marco, Schwarz, Christian, William Zerges (95563)   +20 more
core   +1 more source