Results 51 to 60 of about 196,311 (276)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Image-Based Analysis Revealing the Molecular Mechanism of Peroxisome Dynamics in Plants

Frontiers in Cell and Developmental Biology, 2022
Peroxisomes are present in eukaryotic cells and have essential roles in various biological processes. Plant peroxisomes proliferate by de novo biosynthesis or division of pre-existing peroxisomes, degrade, or replace metabolic enzymes, in response to ...
Shino Goto-Yamada, Kazusato Oikawa, Katsuyuki T. Yamato, Masatake Kanai, Kazumi Hikino, Mikio Nishimura, Shoji Mano, Shoji Mano   +7 more
doaj   +1 more source

Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance

, 2015
Additional supplementary file for eLife article "Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance" (2014, eLife 2014;3:e02678, doi: 10.7554/eLife.02678).
eLife Sciences (710207), Shankar Mukherji (828635), Erin K O'Shea (55441)   +2 more
core   +1 more source

A predicted physicochemically distinct sub-proteome associated with the intracellular organelle of the anammox bacterium Kuenenia stuttgartiensis [PDF]

, 2010
Medema MH, Zhou M, van Hijum SAFT, et al. A predicted physicochemically distinct sub-proteome associated with the intracellular organelle of the anammox bacterium Kuenenia stuttgartiensis. BMC Genomics.
Sacha A.F.T. van Hijum, Gloerich, J., Zhou, M., Wessels, Hans J. C. T, Strous Marc, Wessels Hans JCT, Jolein Gloerich, Strous, Marc, Medema, M.H., Gloerich Jolein, Marc Strous, van Hijum, Sacha A. F. T., van Hijum Sacha AFT, Gloerich, Jolein, Zhou Miaomiao, Siezen Roland J, Siezen, Roland J., Strous, M., Hans J.C.T Wessels, Hijum, S.A.F.T. van, Roland J. Siezen, Wessels, H.C.T., Medema, Marnix H., Marnix H. Medema, Siezen, R.J., Zhou, Miaomiao, Miaomiao Zhou, Medema Marnix H   +27 more
core   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The evolution of per-cell organelle number

Frontiers in Cell and Developmental Biology, 2016
Organelles with their own distinct genomes, such as plastids and mitochondria, are found in most eukaryotic cells. As these organelles and their host cells have evolved, the partitioning of metabolic processes and the encoding of interacting gene ...
Logan W. Cole
doaj   +1 more source

Yeast peroxisomes: function and biogenesis of a versatile cell organelle [PDF]

, 1997
Yeast peroxisomes harbour enzymes involved in the metabolism of specific growth substrates. Sequestration of these enzymes increases the efficiency of such pathways. Currently, 16 genes involved in peroxisome biogenesis have been identified, and analysis
Veenhuis, M, Veenhuis, Marten,, van der Klei, IJ; id_orcid, Klei, Ida J. van der,, van der Klei, IJ   +4 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Lipid droplets and small extracellular vesicles: More than two independent entities

Journal of Extracellular Biology
Despite increasing knowledge about small extracellular vesicle (sEV) composition and functions in cell–cell communication, the mechanism behind their biogenesis remains unclear.
Géraldine C. Genard, Luca Tirinato, Francesca Pagliari, Jessica Da Silva, Alessandro Giammona, Fatema Alquraish, Maria Parra Reyes, Marie Bordas, Maria Grazia Marafioti, Simone Di Franco, Jeannette Janssen, Daniel Garcia‐Calderón, Rachel Hanley, Clelia Nistico, Yoshinori Fukasawa, Torsten Müller, Jeroen Krijgsveld, Matilde Todaro, Francesco Saverio Costanzo, Giorgio Stassi, Michelle Nessling, Karsten Richter, Kendra K. Maass, Carlo Liberale, Joao Seco   +24 more
doaj   +1 more source

The Effect of Moderate and High Intensity Resistance Training on the Expression of PGC-1α, TFAM and AMPK of Cardiomyocytes in Elderly Rats

Journal of Ardabil University of Medical Sciences, 2021
Background & objectives: Age-related cardiovascular dysfunction is often accompanied by impaired mitochondrial biogenesis and function. Exercise training can improve mitochondrial function and content in muscle to meet the energy demands of the cells ...
Rohollah Taheri Gandomani, Bahman Mirzaei, Arssalan Damirchi   +2 more
doaj