Reperfusion promotes mitochondrial biogenesis following focal cerebral ischemia in rats. [PDF]
PLoS ONE, 2014 BACKGROUND AND PURPOSE: Reperfusion after transient cerebral ischemia causes severe damage to mitochondria; however, little is known regarding the continuous change in mitochondrial biogenesis during reperfusion.
Yuying Xie +4 more
doaj +1 more source
Progress in Nonalcoholic Fatty Liver Disease: SIRT Family Regulates Mitochondrial Biogenesis
Biomolecules, 2022 Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin resistance, mitochondrial dysfunction, inflammation, and oxidative stress.
Chuanfei Zeng, Mingkai Chen
semanticscholar +1 more source
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. [PDF]
PLoS ONE, 2008 DNA damage such as double-stranded DNA breaks (DSBs) has been reported to stimulate mitochondrial biogenesis. However, the underlying mechanism is poorly understood. The major player in response to DSBs is ATM (ataxia telangiectasia mutated).
Xuan Fu +4 more
doaj +1 more source
Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis
Signal Transduction and Targeted Therapy, 2021 In addition to their use in relieving the symptoms of various diseases, ketogenic diets (KDs) have also been adopted by healthy individuals to prevent being overweight. Herein, we reported that prolonged KD exposure induced cardiac fibrosis.
Sha Xu +8 more
semanticscholar +1 more source
Evaluation of fisetin as a potential inducer of mitochondrial biogenesis in SH-SY5Y neuronal cells [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Increasing evidence implicates impaired mitochondrial biogenesis as an important contributor to mitochondrial dysfunction, which plays a central role in the pathogenesis of neurodegenerative diseases including Parkinson’s disease (PD).
Muhammet Ay
doaj +1 more source
Targeting Mitochondrial Biogenesis with Polyphenol Compounds
Oxidative Medicine and Cellular Longevity, 2021 Appropriate mitochondrial physiology is an essential for health and survival. Cells have developed unique mechanisms to adapt to stress circumstances and changes in metabolic demands, by meditating mitochondrial function and number.
Leila Chodari +8 more
semanticscholar +1 more source
Effects of Dietary Terpinen-4-ol on Oxidative Stress and Mitochondrial Biogenesis in the Liver of Broilers with Pulmonary Hypertension Syndrome [PDF]
Int J Mol SciXinyue Jiang +8 more
europepmc +3 more sources
Biology, 2021 The five-sixth nephrectomy (5/6Nx) model is widely used to study the mechanisms involved in chronic kidney disease (CKD) progression. Mitochondrial impairment is a critical mechanism that favors CKD progression.
Rodrigo Prieto-Carrasco +8 more
doaj +1 more source
Mitochondrial Biogenesis, Mitochondrial Dynamics, and Mitophagy in the Maturation of Cardiomyocytes
Cells, 2021 Pluripotent stem cells (PSCs) can undergo unlimited self-renewal and can differentiate into all the cell types present in our body, including cardiomyocytes.
Qianqian Ding, Yanxiang Qi, S. Tsang
semanticscholar +1 more source
Oxidative Medicine and Cellular Longevity, 2021 Background The mitochondrial dynamics and mitochondrial biogenesis are essential for maintaining the bioenergy function of mitochondria in diabetic cardiomyopathy (DCM).
Tianyi Ma +9 more
semanticscholar +1 more source