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Mitochondrial Dynamics in Mammals
, 2004 This chapter discusses the role of mitochondria dynamics in mammalian mitochondrial morphology, mitochondrial function, disease, embryogenesis, and apoptosis. It defines mitochondria as static, kidney bean-shaped organelles that have the mundane chore of providing energy for the cell.
Chen, Hsiuchen, Chan, David C.
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2010
Mitochondrial dynamics is a key feature for the interaction of mitochondria with other organelles within a cell and also for the maintenance of their own integrity. Four types of mitochondrial dynamics are discussed: Movement within a cell and interactions with the cytoskeleton, fusion and fission events which establish coherence within the chondriome,
Jürgen, Bereiter-Hahn, Marina, Jendrach
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Mitochondrial dynamics is a key feature for the interaction of mitochondria with other organelles within a cell and also for the maintenance of their own integrity. Four types of mitochondrial dynamics are discussed: Movement within a cell and interactions with the cytoskeleton, fusion and fission events which establish coherence within the chondriome,
Jürgen, Bereiter-Hahn, Marina, Jendrach
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MITOCHONDRIAL DYNAMICS IN YEAST
Annual Review of Cell and Developmental Biology, 1998▪ Abstract Proteins that control mitochondrial dynamics in yeast are being identified at a rapid pace. These proteins include cytoskeletal elements that regulate organelle distribution and inheritance and several outer membrane proteins that are required to maintain the branched, mitochondrial reticulum.
G J, Hermann, J M, Shaw
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The regulation of mitochondrial dynamics
Current Opinion in Cell Biology, 2014The structure of mitochondria is highly dynamic. Mitochondrial shape is cell-type specific and can be modified to meet changing requirements in energy production, calcium homeostasis, lipid biogenesis, fatty acid synthesis and other mitochondrial activities.
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The influence of mitochondrial dynamics on mitochondrial genome stability
Current Genetics, 2017Mitochondria are dynamic organelles that fuse and divide. These changes alter the number and distribution of mitochondrial structures throughout the cell in response to developmental and metabolic cues. We have demonstrated that mitochondrial fission is essential to the maintenance of mitochondrial DNA (mtDNA) under changing metabolic conditions in ...
Christopher T, Prevost +6 more
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Mitochondrial dynamics and inter-mitochondrial communication in the heart
Archives of Biochemistry and Biophysics, 2019Mitochondria are organelles highly dynamic in most types of cells, constantly changing morphology and forming dynamically continuous networks. Defects of mitochondrial dynamics are associated with various human diseases including neurodegenerative diseases and cardiovascular diseases.
Yang-Po, Cao, Ming, Zheng
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Mitochondrial Dynamics in Disease
New England Journal of Medicine, 2007Mitochondria are subcellular organelles that coordinate numerous metabolic reactions, including those of the respiratory complexes that produce the ATP that powers cellular reactions. They have often been depicted as static, with a kidney-bean shape, but there is a growing appreciation of their dynamic nature.
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Mitochondrial dynamics in filamentous fungi
Fungal Genetics and Biology, 2002Mitochondria are essential organelles of eukaryotic cells. They grow continuously throughout the cell cycle and are inherited by daughter cells upon cell division. Inheritance of mitochondria and maintenance of mitochondrial distribution and morphology require active transport of the organelles along the cytoskeleton and depend on membrane fission and ...
Benedikt, Westermann, Holger, Prokisch
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Mitochondrial morphology is dynamic and varied
Molecular and Cellular Biochemistry, 2004The morphology of mitochondria is dynamic, often changing within a cell and from one cell type to the next. In the past few years, significant advances have been made in the study of mechanisms that help determine the morphologies of mitochondria and their intracellular distributions.
Daniel A, Rube +1 more
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Mitochondrial Dynamics and Metabolic Regulation
Trends in Endocrinology & Metabolism, 2016Mitochondrial morphology varies tremendously across cell types and tissues, changing rapidly in response to external insults and metabolic cues, such as nutrient status. The many functions of mitochondria have been intimately linked to their morphology, which is shaped by ongoing events of fusion and fission of outer and inner membranes (OM and IM ...
Wai, Timothy, Langer, Thomas
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