Results 261 to 270 of about 77,225 (305)

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

Aging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu, Gang Ning, Mintao Jian, Ajian Peng, Haoyu Wang, Bonan Li, Xing Zhou   +6 more
wiley   +1 more source

Estrogen receptor β deficiency increases the susceptibility to ulcerative colitis by inducing mitochondrial fission and consequently accelerating senescence of colonic epithelial cells. [PDF]

Redox Biol
Guo Y, He Y, Zhu Y, Zhang W, Lin H, Zhao M, Zhang J, Bai Y, Wei Z, Xia Y, Dai Y.   +10 more
europepmc   +1 more source

Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity. [PDF]

PLoS Genet
Yang X, Wei R, Meng F, Liu D, Gong X, Ruvkun G, Wei W.   +6 more
europepmc   +1 more source

Suppression of Rho-associated kinase 1 (ROCK1) promotes human hematopoietic stem cell expansion by attenuating mitochondrial fission. [PDF]

Leukemia
Wang X, Ramdas B, Kumar R, Zhang J, Kapur R, Kapur R.   +5 more
europepmc   +1 more source

The role of axonopathy in Parkinson\u27s disease [PDF]

, 2010
O’Malley, Karen L
core   +1 more source

Mitochondrial fission process 1 protein: a comprehensive review of its core roles in mitochondrial dynamics, disease, and therapeutic targets. [PDF]

Front Cell Dev Biol
Ran Q, Gao C, Xiang C, He X, Zhang Y, Zhang Y, Chen H.   +6 more
europepmc   +1 more source

Inhibition of DRP1-mediated Mitochondrial Fission and NRF2/HO-1/GPX4-mediated Ferroptosis by Mdivi-1 Protects Against Vascular Cognitive Impairment. [PDF]

Mol Neurobiol
Liu XM, Chen F, Cheng YJ, Wang DP.
europepmc   +1 more source

PHLPP1 regulates region-specific astroglial mitochondrial fission in response to oxidative stress in the male rat hippocampus. [PDF]

Sci Rep
Kim JE, Wang SH, Kang TC.
europepmc   +1 more source

Inhibition of mitochondrial fission protein Drp1 ameliorates skeletal myopathy in the D2-mdx model of Duchenne muscular dystrophy. [PDF]

Am J Physiol Cell Physiol
Rosen HG, Berger NJ, Hodge SN, Fujishiro A, Lourie J, Kapadia V, Duzz T, Linden MA, Jee E, Kim J, Kim Y, Zou K.   +11 more
europepmc   +1 more source

Publisher Correction: Suppression of Rho-associated kinase 1 (ROCK1) promotes human hematopoietic stem cell expansion by attenuating mitochondrial fission. [PDF]

Leukemia
Wang X, Ramdas B, Kumar R, Zhang J, Kapur R.   +4 more
europepmc   +1 more source