Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment
MedComm, Volume 7, Issue 7, July 2026.Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui +5 more
wiley +1 more source
Malic Enzyme 2 Regulates Dynamin-Related Protein 1-Dependent Mitochondrial Fission and Mitochondria-Associated Membranes to Drive Odontogenic Differentiation: An In Vitro and In Vivo Study. [PDF]
BiomoleculesLi J +7 more
europepmc +1 more source
Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management
MedComm, Volume 7, Issue 7, July 2026.Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu +8 more
wiley +1 more source
Questions and comments on "ALKBH5 attenuates mitochondrial fission and ameliorates liver fibrosis by reducing Drp1 methylation," published in Pharmacological Research (2023). [PDF]
Pharmacol ResBai B, Bao W, Wang L, Kang N.
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Mass spectrometry proteomics for studying mitostasis
Protein Science, Volume 35, Issue 7, July 2026.Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma +5 more
wiley +1 more source
Protein Science, Volume 35, Issue 7, July 2026.Abstract Mitochondria import the majority of their proteins from the cytosol, creating a fundamental challenge: precursor proteins must be synthesized, maintained in an import‐competent state, and delivered to mitochondrial translocases without premature folding or aggregation. While mitochondrial protein import has been considered a post‐translational
Nikita A. Kvasov, Yury S. Bykov
wiley +1 more source
MAPK15 Attenuates Intestinal Epithelial Cell Senescence-Like Phenotype to Regulate Gut Homeostasis and Inflammation by Phosphorylating Suz12 to Suppress Drp1-Mediated Mitochondrial Fission Damage. [PDF]
InflammationLi J, Chen G, Bao X.
europepmc +1 more source
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
Environmental Toxicology, Volume 41, Issue 7, Page 416-458, July 2026.ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
WDR63 enhances the chondrogenic differentiation and regenerative potential of stem cell from apical papilla by facilitating vimentin function to promote mitochondrial fission. [PDF]
Stem Cell Res TherZhou J +5 more
europepmc +1 more source