Mitochondrial fission factor drives an actionable metabolic vulnerability in multiple myeloma. [PDF]
Cantafio MEG +19 more
europepmc +1 more source
Astaxanthin mitigates cardiac toxicity induced via doxorubicin by alleviating mitochondrial fission and autophagy in rats. [PDF]
He Y +8 more
europepmc +1 more source
Plant-specific mitochondrial fission machinery connects mitochondrial dynamics and mitophagosome formation for piecemeal mitophagy. [PDF]
Ma J +10 more
europepmc +1 more source
Correction: Reciprocal regulation of oxidative stress and mitochondrial fission augments parvalbumin downregulation through CDK5-DRP1- and GPx1-NF-κB signaling pathways. [PDF]
Wang SH +4 more
europepmc +1 more source
The mitochondrial E3 ligase MAPL SUMOylates Drp1 to facilitate mitochondrial fission in intervertebral disc degeneration. [PDF]
Lin Z +11 more
europepmc +1 more source
Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity. [PDF]
Voos KM +9 more
europepmc +1 more source
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Function and regulation of the divisome for mitochondrial fission
Nature, 2021Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative fusion and fission events of the organelles. It is now appreciated that mitochondrial fission also represents an end-point event in a signalling axis that allows cells to sense and respond to external cues.
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Mitochondrial fission and fusion
Biochemical Society Transactions, 2016Mitochondrial fission and fusion have been recognized as critical processes in the health of mitochondria and cells. Two decades of studies have generated a great deal of information about mitochondrial fission and fusion; however, still much needs to be understood for the basic molecular mechanisms of these important cellular processes.
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Mitochondrial fission in apoptosis
Nature Reviews Molecular Cell Biology, 2005Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.
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Mitochondrial fission fueled by fasting
Science Signaling, 2023Fasting activates mTORC2 to stimulate mitochondrial fission and support mitochondrial respiration.
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