Results 221 to 230 of about 77,225 (305)

β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition. [PDF]

Mil Med Res
Wang XX, Zhong WJ, Li JM, Wang D, Chen SQ, Miao JH, Shen WW, Li XL, Huang JW, Zhou S, Wang C, Ai J, Zhou LL.   +12 more
europepmc   +1 more source

Mitochondrial reprogramming in lung cancer: a therapeutic vulnerability and a strategy for reversing drug resistance

The Journal of Pathology, Volume 269, Issue 2, Page 149-163, June 2026.
Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley   +1 more source

Correction: Reciprocal regulation of oxidative stress and mitochondrial fission augments parvalbumin downregulation through CDK5-DRP1- and GPx1-NF-κB signaling pathways. [PDF]

Cell Death Dis
Wang SH, Lee DS, Kim TH, Kim JE, Kang TC.   +4 more
europepmc   +1 more source

Molecular Machinery of Mitochondrial Fusion and Fission [PDF]

Journal of Biological Chemistry, 2008
openaire   +2 more sources

Structural analysis of Cu/Zn‐superoxide dismutase linked to neurodegenerative disease by antibody‐guided cryo‐EM

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Accumulation of misfolded proteins is a hallmark of many neurodegenerative diseases. To characterize such misfolded species in vivo, conformation‐specific antibodies are widely used; however, limited knowledge of antibody–epitope interactions often hampers mechanistic insight.
Yuki Shino, Norifumi Muraki, Yui Kobatake, Hiroaki Kamishina, Hirofumi Kosuge, Makoto Nakakido, Kouhei Tsumoto, Yoshiaki Furukawa   +7 more
wiley   +1 more source

Phosphodiesterase 4 (PDE 4) Inhibition Reduces Ischemia-Reperfusion-Induced Leucocyte Infiltration, Apoptosis and Mitochondrial Fission Markers in Mice Skeletal Muscles Four Hours After Ischemia Onset. [PDF]

Muscles
Charles AL, Tetsi L, Quiring G, Barnig C, Giannini M, Meyer A, Lejay A, Lugnier C, Geny B.   +8 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, Volume 16, Issue 5, Page 885-905, May 2026.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

During <i>Aspergillus nidulans</i> nitrogen-limited biofilm formation, mitophagy is independent of mitochondrial fission. [PDF]

Autophagy Rep
Balasubramanian HK, Osmani SA.
europepmc   +1 more source

Bioinspired, Mitochondria‐Targeted Single‐Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

Advanced Materials, Volume 38, Issue 26, 8 May 2026.
A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang, Xinzhi Liang, Tiandi Xiong, Zheng Zhong, Ning Zhang, Boguang Yang, Dong Li, Qiongjiao Zeng, Xian Chen, Yiting Lei, Shangsi Chen, Chao Zheng, Liu Yang, Wei Huang, Rocky S. Tuan, Denghui Xie, Zhong Alan Li   +16 more
wiley   +1 more source