Results 211 to 220 of about 43,432 (263)

Retraction Note: TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway. [PDF]

Cancer Cell Int
Ji K, Lin K, Wang Y, Du L, Xu C, He N, Wang J, Liu Y, Liu Q.   +8 more
europepmc   +1 more source

Paeoniflorin and NAFLD: A Systematic Review and Meta‐Analysis of Animal Studies With Mechanistic Insights

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Evidence from 10 preclinical studies involving 181 rodents indicates that paeoniflorin may alleviate several features of nonalcoholic fatty liver disease, including dyslipidemia, impaired glucose metabolism, liver injury, inflammation, and oxidative stress.
Dachuan Jin, Shunqin Jin, Tao Zhou, Guoping Sheng, Mingfei Yao, Peng Gao, Guangming Li, Chuan Qin   +7 more
wiley   +1 more source

Superoxide Anion-Dependent Mitochondrial Fission Contributes to Hippocampal Synaptic Dysfunction in Stress-Susceptible Mice. [PDF]

JACS Au
Li X, Xue X, Zhang S, James TD, Li P, Wang X, Tang B.   +6 more
europepmc   +1 more source

β‐Elemene Triggers Drp1‐Dependent Mitochondrial Fission Through CDK1/Cyclin B1 Signaling in Cervical Cancer Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This study reveals a novel molecular mechanism by which the natural sesquiterpene β‐Elemene exerts anti‐tumor effects in cervical cancer. β‐Elemene treatment promotes the activation of the CDK1/Cyclin B1 kinase complex. Activated CDK1/Cyclin B1, in turn, phosphorylates the mitochondrial fission protein Drp1 at serine 616.
Zhifang Li, Ling Tang, Mingyan Wang, Qiong Yu, Chen Chen, Jiyi Xia, Xiaolan Yu   +6 more
wiley   +1 more source

β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition. [PDF]

Mil Med Res
Wang XX, Zhong WJ, Li JM, Wang D, Chen SQ, Miao JH, Shen WW, Li XL, Huang JW, Zhou S, Wang C, Ai J, Zhou LL.   +12 more
europepmc   +1 more source

Myocardial Lipid Metabolism Imbalance: The Pathological Core and Novel Diagnostic‐Therapeutic Directions of Cardiovascular Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie, Qun Zeng, Hongrui Wang, Meihua She   +3 more
wiley   +1 more source

Mitochondrial fission - changing perspectives for future progress.

J Cell Sci
Kamerkar SC, Liu A, Higgs HN.
europepmc   +1 more source

During <i>Aspergillus nidulans</i> nitrogen-limited biofilm formation, mitophagy is independent of mitochondrial fission. [PDF]

Autophagy Rep
Balasubramanian HK, Osmani SA.
europepmc   +1 more source

SRM 1650b Administration to Isolated Rat Heart Aggravates Ischemia‐Reperfusion Injury via Mitochondrial Dysfunction and Downregulation of PI3K/Akt Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
SRM 1650b diesel particulate matter caused dose‐dependent cardiotoxicity in isolated male Wistar rat hearts, worsening hemodynamics and tissue injury after ischemia–reperfusion. It increased oxidative stress, impaired mitochondrial bioenergetics and respiration, downregulated mitochondrial quality‐control genes, reduced mtDNA copy number, and ...
Kirankumar Balu, Uvasshri Vijayakumar, Bhavana Sivakumar, Priyanka N. Prem, Gino A. Kurian   +4 more
wiley   +1 more source