Measuring mitochondrial membrane potential [PDF]
The EMBO JournalMitochondrial function determines the balance between health and disease, making understanding their bioenergetics an increasingly important focus across biomedical research.
Oscar Tovar-Ferrero +4 more
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Thioflavin T indicates mitochondrial membrane potential in mammalian cells [PDF]
Biophysical Reports, 2023 The fluorescent benzothiazole dye thioflavin T (ThT) is widely used as a marker for protein aggregates, most commonly in the context of neurodegenerative disease research and diagnosis.
Emily Skates +4 more
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Mitochondrial Membrane Potential Predicts 4-Hour Sperm Motility [PDF]
Biomedicines, 2020 The evaluation of conventional and biofunctional sperm parameters is of fundamental importance for assessing male reproductive function. Among these, sperm motility is one of the most important parameters. Indeed, asthenozoospermia is a frequent cause of
Angela Alamo +7 more
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Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors [PDF]
Frontiers in Pharmacology, 2021 Mitochondria are the main bioenergetic organelles of cells. Exposure to chemicals targeting mitochondria therefore generally results in the development of toxicity. The cellular response to perturbations in cellular energy production is a balance between
Huan Yang +8 more
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Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus [PDF]
Frontiers in Molecular BiosciencesBackgroundMitochondrial dysfunction is implicated in the pathogenesis of systemic lupus erythematosus (SLE). Single-cell mitochondrial mass (SCMM), low mitochondrial membrane potential (MMP-Low) in lymphocytes, and circulating mitochondrial DNA (mtDNA ...
Guanfei Zhao +11 more
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Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms [PDF]
eLifeMitochondrial membrane potential directly powers many critical functions of mitochondria, including ATP production, mitochondrial protein import, and metabolite transport.
Yeyun Ouyang +19 more
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Analysis of mitochondrial membrane potential, ROS, and calcium [PDF]
Molecules and Cells: Mitochondria play a central role in cellular energy metabolism and signaling, and their dysfunction is associated with a wide range of diseases. Therefore, assessing mitochondrial function is essential for understanding their role in various cellular ...
Hye-Kyung Park, Byoung Heon Kang
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Implications of mitochondrial membrane potential gradients on signaling and ATP production analyzed by correlative multi-parameter microscopy [PDF]
Scientific ReportsThe complex architecture and biochemistry of the inner mitochondrial membrane generate ultra-structures with different phospholipid and protein compositions, shapes, characteristics, and functions.
Benjamin Gottschalk +3 more
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Arabidopsis thaliana Embryo Sac Mitochondrial Membrane Potential Stain [PDF]
Bio-Protocol, 2014 The aim of this experiment is to study mitochondrial functional status in Arabidopsis embryo sacs using the membrane potential indicator JC-1. Changes in the membrane potential are presumed to be due to the opening of the mitochondrial permeability ...
María Martin +3 more
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Frontiers in Cell and Developmental Biology, 2022 Mitochondria are biosynthetic, bioenergetic, and signaling organelles with a critical role in cellular physiology. Dysfunctional mitochondria are associated with aging and underlie the cause of a wide range of diseases, from neurodegeneration to cancer ...
Karthik Vasan +7 more
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