Results 11 to 20 of about 350,705 (311)

Legionella pneumophila secretes a mitochondrial carrier protein during infection.

PLoS Pathogens, 2012
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M T Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow   +16 more
doaj   +1 more source

Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in a Cell Free System from Neurospora crassa [PDF]

, 1977
Synthesis and transport of mitochondrial proteins were followed in a cell-free homogenate of Neurospora crassa in which mitochondrial translation was inhibited. Proteins synthesized on cytoplasmic ribosomes are transferred into the mitochondrial fraction.
Andrews T. M., Bingham R. W., Blair G. E., Davidian N. M., Dobberstein B., Dolken G., Gaitskhoki V. S., Godinot C., Gonzalez-Cadavid N. F., Gonzalez-Cadavid N. F., Grollmann A. P., Hallermayer G., Kadenbach B., Kadenbach B., Kadenbach B., Kellems R. E., Kellems R. E., Kellems R. E., Kellems R. E., Marra E., Milstein C., Morris A., O'Brien R. L., Pfaff E., Redman C. M., Shore G. C., Takanami M., Tata J. R., Weiss H., Wojtczak L., Wojtczak L.   +30 more
core   +1 more source

Biogenesis of mitochondrial porin [PDF]

, 1990
We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins.
A. Grossmann, A. L. Horwich, B. L. Geller, B. Schmidt, C. Smagula, C. Witte, C. Zwizinski, C. Zwizinski, D. M. Kolansky, D. Roise, D. Vestweber, D. W. Nicholson, E. C. Hurt, E. C. Hurt, E. C. Hurt, E. C. Hurt, F.-U. Hartl, G. Hallermayer, G. Hawlitschek, G. Heijne von, G. S. Adrian, H. Aquila, H. Aquila, H. Freitag, H. Freitag, H. Freitag, H. Murakami, H. Ono, H. Wiech, J. A. Rothblatt, K. Mihara, K. Mihara, L. Chen, M. Colombini, M. Eilers, M. Eilers, M. G. Waters, M. Linden, M. Mueckler, M. P. Yaffe, M. Schleyer, M. Schleyer, M. Schwaiger, M. Y. Cheng, M. Yang, N. Pfanner, N. Pfanner, N. Pfanner, N. Pfanner, N. Pfanner, N. Pfanner, N. Pflanner, R. A. Pollock, R. A. Stuart, R. Benz, R. E. Jensen, R. J. Deshaies, R. Jaenicke, R. Kleene, R. Kleene, R. Pfaller, R. Pfaller, R. Pfaller, R. Pfaller, R. Zimmermann, S. Hamajima, S. M. Gasser, S. M. Gasser, T. Hase, T. Imanaka, U. I. Flügge, W. Hansen, W. J. Chirico, W. Neupert, W.-J. Chen   +74 more
core   +1 more source

Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport

Molecular Metabolism, 2020
Objective: Cholesterol plays a pivotal role in mitochondrial steroidogenesis, membrane structure, and respiration. Mitochondrial membranes are intrinsically low in cholesterol content and therefore must be replenished with cholesterol from other ...
John-Paul Andersen, Jun Zhang, Haoran Sun, Xuyun Liu, Jiankang Liu, Jia Nie, Yuguang Shi   +6 more
doaj   +1 more source

Transport of proteins into mitochondria [PDF]

, 1985
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Neupert, Walter, Schleyer, Manfred
core   +1 more source

Transport of proteins across or into the mitochondrial outer membrane

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010
Mitochondria are surrounded by two biological membranes. The outer mitochondrial membrane contains two major translocators, the TOM40 (TOM) and TOB/SAM complexes for protein translocation across and/or insertion into the outer membrane. The TOM40 complex functions as an entry gate for most mitochondrial proteins, and the TOB/SAM complex as a ...
Endo, Toshiya, Yamano, Koji
openaire   +2 more sources

The SPFH Protein Superfamily in Fungi: Impact on Mitochondrial Function and Implications in Virulence

Microorganisms, 2021
Integral membrane proteins from the ancient SPFH (stomatin, prohibitin, flotillin, HflK/HflC) protein superfamily are found in nearly all living organisms.
Marienela Y. Heredia, Jason M. Rauceo
doaj   +1 more source

Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]

, 1993
Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
Lill, Roland, Mayer, Andreas, Neupert, Walter   +2 more
core   +2 more sources

Protein transport machineries for precursor translocation across the inner mitochondrial membrane

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
The mitochondrial inner membrane has a central function for the energy metabolism of the cell. The respiratory chain generates a proton gradient across the inner mitochondrial membrane, which is used to produce ATP by the F1Fo-ATPase. To maintain the electrochemical gradient, the inner membrane represents an efficient permeability barrier for small ...
Wagner, Karina, Mick, David U., Rehling, Peter   +2 more
openaire   +3 more sources

Niemann-Pick Type C2 protein contributes to the transport of endosomal cholesterol to mitochondria without interacting with NPC1[S]

Journal of Lipid Research, 2012
Mitochondrial cholesterol is maintained within a narrow range to regulate steroid and oxysterol synthesis and to ensure mitochondrial function. Mitochondria acquire cholesterol through several pathways from different cellular pools.
Barry E. Kennedy, Mark Charman, Barbara Karten   +2 more
doaj   +1 more source