Results 21 to 30 of about 350,705 (311)
Contact, 2023 Numerous studies have revealed that organelle membrane contact sites (MCSs) play important roles in diverse cellular events, including the transport of lipids and ions between connected organelles.
Shintaro Fujimoto +2 more
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Mitochondrial protein import [PDF]
, 1994 The transport of nuclear-encoded proteins from the cytosol into mitochondria is mediated by targeting (signal) sequences present on precursor forms.
Neupert, Walter, Schwarz, Elisabeth
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Formation and Regulation of Mitochondrial Membranes
International Journal of Cell Biology, 2014 Mitochondrial membrane phospholipids are essential for the mitochondrial architecture, the activity of respiratory proteins, and the transport of proteins into the mitochondria.
Laila Cigana Schenkel, Marica Bakovic
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009 The yeast proteins Mrs3p and Mrs4p are two closely related members of the mitochondrial carrier family (MCF), which had previously been implicated in mitochondrial Fe(2+) homeostasis. A vertebrate Mrs3/4 homologue named mitoferrin was shown to be essential for erythroid iron utilization and proposed to function as an essential mitochondrial iron ...
Froschauer-Neuhauser, Elisabeth +2 more
openaire +3 more sources
BMC Biology, 2018 Background Bacteria and mitochondria contain translocases that function to transport proteins across or insert proteins into their inner and outer membranes. Extant mitochondria retain some bacterial-derived translocases but have lost others.
Markéta Petrů +5 more
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Miro proteins and their role in mitochondrial transfer in cancer and beyond
Frontiers in Cell and Developmental Biology, 2022 Mitochondria are organelles essential for tumor cell proliferation and metastasis. Although their main cellular function, generation of energy in the form of ATP is dispensable for cancer cells, their capability to drive their adaptation to stress ...
Zuzana Nahacka +5 more
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TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control [PDF]
, 2014 The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane (OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits mitochondrial autophagy downstream of the PINK1-PARK2 pathway, preventing essential ...
Anholt R +22 more
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Dual Role of Mitochondrial Porin in Metabolite Transport across the Outer Membrane and Protein Transfer to the Inner Membrane [PDF]
Molecular Cell, 2019 The mitochondrial inner membrane harbors a large number of metabolite carriers. The precursors of carrier proteins are synthesized in the cytosol and imported into mitochondria by the translocase of the outer membrane (TOM) and the carrier translocase of the inner membrane (TIM22). Molecular chaperones in the cytosol and intermembrane space bind to the
Ellenrieder, Lars +7 more
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F1000Research, 2013 In kinetoplastid protists, several metabolic pathways, including glycolysis and purine salvage, are located in glycosomes, which are microbodies that are evolutionarily related to peroxisomes.
Claudia Colasante +6 more
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The plant mitochondrial carrier family: functional and evolutionary aspects
Frontiers in Plant Science, 2012 Mitochondria play a key role in respiration and energy production and are involved in multiple eukaryotic but also in several plant specific metabolic pathways. Solute carriers in the inner mitochondrial membrane connect the internal metabolism with that
Ilka eHaferkamp, Stephan eSchmitz-Esser
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