Mitochondrial Membranes and Mitochondrial Genome: Interactions and Clinical Syndromes [PDF]
Membranes, 2022 Mitochondria are surrounded by two membranes; the outer mitochondrial membrane and the inner mitochondrial membrane. They are unique organelles since they have their own DNA, the mitochondrial DNA (mtDNA), which is replicated continuously.
Mohammed Almannai +2 more
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Amyloid pores in mitochondrial membranes
Neural Regeneration Research, 2021 Neville Vassallo
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Effect of Fusidic Acid and Some Nitrogen-Containing Derivatives on Liposomal and Mitochondrial Membranes [PDF]
Membranes, 2023 The paper assesses the membranotropic action of the natural antibiotic fusidic acid (FA) and its derivatives. It was found that a FA analogue with ethylenediamine moiety (derivative 2), in contrast to native FA and 3,11-dioxime analogue (derivative 1 ...
Mikhail V. Dubinin +7 more
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Two domains of Tim50 coordinate translocation of proteins across the two mitochondrial membranes [PDF]
Life Science Alliance, 2023 Biochemical and genetic experiments identify distinct roles of the two domains of Tim50 in the intermembrane space during translocation of proteins into the mitochondria via the TOM and TIM23 complexes.
Marcel G Genge +7 more
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Coordinated Translocation of Presequence-Containing Precursor Proteins Across Two Mitochondrial Membranes: Knowns and Unknowns of How TOM and TIM23 Complexes Cooperate With Each Other [PDF]
Frontiers in Physiology, 2022 The vast majority of mitochondrial proteins are encoded in the nuclear genome and synthesized on cytosolic ribosomes as precursor proteins with specific mitochondrial targeting signals. Mitochondrial targeting signals are very diverse, however, about 70%
Marcel G. Genge, Dejana Mokranjac
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Dynamic Imaging of Lipid Order and Heterogeneous Microviscosity in Mitochondrial Membranes of Potato Tubers Under Abiotic Stress [PDF]
MembranesMicroviscosity and lipid order are the main parameters characterizing the phase states of the membrane. Variations in microviscosity and lipid composition in a living cell may indicate serious disturbances, including various kinds of stress. In this work,
Vadim N. Nurminsky +5 more
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Incorporation of Omega-3 Fatty Acids Into Human Skeletal Muscle Sarcolemmal and Mitochondrial Membranes Following 12 Weeks of Fish Oil Supplementation [PDF]
Frontiers in Physiology, 2019 Fish oil (FO) supplementation in humans results in the incorporation of omega-3 fatty acids (FAs) eicosapentaenoic acid (EPA; C20:5) and docosahexaenoic acid (DHA; C20:6) into skeletal muscle membranes.
Christopher J. Gerling +7 more
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Naja naja oxiana Cobra Venom Cytotoxins CTI and CTII Disrupt Mitochondrial Membrane Integrity: Implications for Basic Three-Fingered Cytotoxins. [PDF]
PLoS ONE, 2015 Cobra venom cytotoxins are basic three-fingered, amphipathic, non-enzymatic proteins that constitute a major fraction of cobra venom. While cytotoxins cause mitochondrial dysfunction in different cell types, the mechanisms by which cytotoxins bind to ...
Sardar E Gasanov +6 more
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The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial Membranes [PDF]
Life, 2020 Mitochondria are complex organelles that harbour their own genome. Mitochondrial DNA (mtDNA) exists in the form of a circular double-stranded DNA molecule that must be replicated, segregated and distributed around the mitochondrial network.
James Chapman +2 more
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Formation and Regulation of Mitochondrial Membranes [PDF]
International Journal of Cell Biology, 2014 Mitochondrial membrane phospholipids are essential for the mitochondrial architecture, the activity of respiratory proteins, and the transport of proteins into the mitochondria.
Laila Cigana Schenkel, Marica Bakovic
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