Results 31 to 40 of about 802,688 (257)

Sorting of exclusive mitochondrial proteins from the Mitoproteome database

Bulletin of the National Research Centre, 2022
World Wide Web and scientific literature record information regarding several organelles and mitochondria is not an exception. However, currently mitochondrial databases also provide information about non-mitochondrial proteins.
Deepak Yadav, Bharti Thakur, Deepak Kumar, Sheemona Chowdhary, Rajasri Bhattacharyya, Dibyajyoti Banerjee   +5 more
doaj   +1 more source

Loss of Drosophila Clueless differentially affects the mitochondrial proteome compared to loss of Sod2 and Pink1

Frontiers in Physiology, 2022
Mitochondria contain their own DNA, mitochondrial DNA, which encodes thirteen proteins. However, mitochondria require thousands of proteins encoded in the nucleus to carry out their many functions.
Aditya Sen, Aditya Sen, Rachel T. Cox
doaj   +1 more source

Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view [PDF]

, 2006
The proper functioning of mitochondria requires that both the mitochondrial and the nuclear genome are functional. To investigate the importance of the mitochondrial genome, which encodes only 13 subunits of the respiratory complexes, the mitochondrial ...
Abdul, Appleby, Armstrong, Bai, Bourges, Buchet, Chai, Claros, Da Cruz, Dey, Du, Garcia, Gianazza, Joseph, King, King, Lescuyer, Luche, Manjasetty, Martinus, Perkins, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Rabilloud, Santoni, Sharma, Sharp, Sherer, Singh, Sinha, Suzuki, Tastet, Taylor, Tryoen-Toth, Ugalde, Wiedemann, Zamzami, Zischka   +39 more
core   +4 more sources

Mechanisms of Modulation of Mitochondrial Architecture

Biomolecules, 2023
Mitochondrial network architecture plays a critical role in cellular physiology. Indeed, alterations in the shape of mitochondria upon exposure to cellular stress can cause the dysfunction of these organelles.
Juan Pablo Muñoz, Fernanda Luisa Basei, María Laura Rojas, David Galvis, Antonio Zorzano   +4 more
doaj   +1 more source

Mitochondrial molecular chaperones [PDF]

, 1994
After synthesis in the cytosol, most mitochondrial proteins must traverse mitochondrial membranes to reach their functional location. During this process, proteins become unfolded and then refold to attain their native conformation after crossing the ...
Atencio, Caplan, Caplan, Cheng, Craig, Cyr, Deshales, Eilers, Gambill, Glick, Glick, Hartl, Hartl, Hwang, Johnson, Kang, Kiebler, Langer, Liberek, Manning-Krieg, Neupert, Ostermann, Palleros, Rassow, Rospert, Sanders, Scherer, Schleyer, Schröder, Simon, Vestweber, Voos, Xia   +32 more
core   +1 more source

Effect of the mitochondrial unfolded protein response on hypoxic death and mitochondrial protein aggregation [PDF]

Cell Death & Disease, 2021
AbstractMitochondria are the main oxygen consumers in cells and as such are the primary organelle affected by hypoxia. All hypoxia pathology presumably derives from the initial mitochondrial dysfunction. An early event in hypoxic pathology in C. elegans is disruption of mitochondrial proteostasis with induction of the mitochondrial unfolded protein ...
Chun-Ling Sun, C. Michael Crowder, Junyi Yan, Seokyung Shin, Seokyung Shin, Marc Van Gilst   +5 more
openaire   +5 more sources

Dual targeted mitochondrial proteins are characterized by lower MTS parameters and total net charge. [PDF]

PLoS ONE, 2008
BACKGROUND: In eukaryotic cells, identical proteins can be located in different subcellular compartments (termed dual-targeted proteins). METHODOLOGY/PRINCIPAL FINDINGS: We divided a reference set of mitochondrial proteins (published single gene studies)
Maya Dinur-Mills, Merav Tal, Ophry Pines
doaj   +1 more source

Targeting and Insertion of Membrane Proteins in Mitochondria

Frontiers in Cell and Developmental Biology, 2021
Mitochondrial membrane proteins play an essential role in all major mitochondrial functions. The respiratory complexes of the inner membrane are key for the generation of energy. The carrier proteins for the influx/efflux of essential metabolites to/from
Ross Eaglesfield, Kostas Tokatlidis
doaj   +1 more source

A morphological view on mitochondrial protein targeting [PDF]

, 1994
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ades, Allmann, Ardail, Ardail, Ardail, Attardi, Baker, Biermans, Biermans, Brdiczka, Brdiczka, Eilers, Glick, Hackenbrock, Hackenbrock, Hackenbrock, Hartl, Hartl, Hines, Hwang, Kellems, Kiebler, Knoll, Lill, Lithgow, Malhotra, Martin, Marzuki, McEnery, Murakami, Nicolay, Ohlendieck, Pain, Pfanner, Pfanner, Pfanner, Pon, Rassow, Rassow, Rassow, Rojo, Schleyer, Schwaiger, Stuart, Suissa, Söllner, Söllner, Söllner, van Venetië, Vestweber, Vestweber, Vignais, Watson, Werner, Wienhues, Zara   +55 more
core   +1 more source

Is ABCC6 a genuine mitochondrial protein? [PDF]

BMC Research Notes, 2013
A recent article in Circulation Research suggests that the protein ABCC6, which when defective is responsible for pseudoxanthoma elasticum, an inherited condition with skin, eye and cardiovascular manifestations, is associated with dysfunction in mitochondria--Martin et al.: ABCC6 Localizes to the Mitochondria-Associated Membrane.Circ Res 2012, 111:516-
Ferré, Marc, Reynier, Pascal, Chevrollier, Arnaud, Prunier-Mirebeau, Delphine, Lefthériotis, Georges, Henrion, Daniel, Bonneau, Dominique, Procaccio, Vincent, Martin, Ludovic   +8 more
openaire   +5 more sources