Results 31 to 40 of about 1,557,014 (330)
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space
Nature Cell Biology, 2023 Mitochondria are complex organelles with different compartments, each harbouring their own protein quality control factors. While chaperones of the mitochondrial matrix are well characterized, it is poorly understood which chaperones protect the ...
Elias Adriaenssens +11 more
semanticscholar +1 more source
Important amino acid residues of potato plant uncoupling protein (StUCP)
Brazilian Journal of Medical and Biological Research, 2000 Chemical modifications were used to identify some of the functionally important amino acid residues of the potato plant uncoupling protein (StUCP). The proton-dependent swelling of potato mitochondria in K+-acetate in the presence of linoleic acid and ...
P. Jezek, A.D.T. Costa, A.E. Vercesi
doaj +1 more source
Rivastigmine prevents injury induced by ischemia and reperfusion in rat liver [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To evaluate whether pre-treatment with rivastigmine is able to attenuate the I/R induced lesions in rat liver. Methods: SHAM animals or those submitted to I/R, non-treated or pre-treated with rivastigminine (2mg/kg) either 50 or 15 minutes ...
Agnaldo Bruno Chies +6 more
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Computational Modeling of In Vitro Swelling of Mitochondria: A Biophysical Approach
Molecules, 2018 Swelling of mitochondria plays an important role in the pathogenesis of human diseases by stimulating mitochondria-mediated cell death through apoptosis, necrosis, and autophagy.
Vladimir I. Makarov +2 more
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Ubiquitin-proteasome dependent mitochondrial protein quality control [PDF]
, 2014 Dysfunctional mitochondria cause many neurodegenerative disorders and with aging in general, mechanisms of mitochondrial quality control are essential for cellular function.
Benischke, Anne-Sophie
core +1 more source
Effect of unsaturated high fatty acid fraction extracted from X-ray irradiated rabbit liver (OX) on the mitochondrial swelling of normal rat liver [PDF]
, 1962 The effects of OX, a high unsaturated fatty acid fraction extracted from x-ray irradiated rabbit liver, on rat liver mitochondrial swelling was studied and following results were obtained.
Urakami, Hiroyuki, Hiroyuki URAKAMI
core +1 more source
Biomedicines, 2021 Mitochondrial dysfunction is currently considered one of the main causes of multiple organ failure in chronic inflammation and sepsis. The participation of microbial metabolites in disorders of bioenergetic processes in mitochondria has been revealed ...
Nadezhda Fedotcheva +2 more
doaj +1 more source
Biochemical Pharmacology, 2017 Current pharmacological treatments for lung cancer show very poor clinical outcomes, therefore, the development of novel anticancer agents with innovative mechanisms of action is urgently needed.
A. M. Rodilla +6 more
semanticscholar +1 more source
Communications Biology, 2023 Mitochondrial dysfunctions are widely afflicted in central nervous system (CNS) disorders with minimal understanding on how to improve mitochondrial homeostasis to promote neuroprotection. Here we have used human stem cell differentiated retinal ganglion
M. Surma +6 more
semanticscholar +1 more source
Mitochondrial swelling induced by Ca2+ and inorganic phosphate and its related phenomena [PDF]
, 1964 Some investigations have been done on the relationships between the swelling-shrinkage change, oxygen consumption and state of oxidation-reduction of pyridine nucleotides of mitochondria, and between the swelling-shrinkage change of mitochondrial ...
Utsumi, Kozo
core +1 more source