Acute treadmill exercise induces mitochondrial unfolded protein response in skeletal muscle of male rats. [PDF]
Turkel I +8 more
europepmc +1 more source
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn +12 more
wiley +1 more source
Mitochondrial unfolded protein response-dependent β-catenin signaling promotes neuroendocrine prostate cancer. [PDF]
Woytash JA +11 more
europepmc +1 more source
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang +10 more
wiley +1 more source
A mitochondrial unfolded protein response-independent role of DVE-1 in longevity regulation. [PDF]
Sheng Y +9 more
europepmc +1 more source
Molecular Links Between Heat Stress and DNA Damage Response in Plants
ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach +1 more
wiley +1 more source
Mechanisms of the Mitochondrial Unfolded Protein Response in Caenorhabditis elegans and Mammals and Its Roles in Striated Muscles. [PDF]
Luan T +11 more
europepmc +1 more source
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
A bird's eye view of mitochondrial unfolded protein response in cancer: mechanisms, progression and further applications. [PDF]
Zhang X, Fan Y, Tan K.
europepmc +1 more source
In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene +4 more
wiley +1 more source

