Results 151 to 160 of about 5,278 (225)
The bacterial dynamin‐like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane association is essential for its protective function, likely preventing explosive membrane rupture following phage infection.
Samia Shafqat +2 more
wiley +1 more source
Programa de Doctorat en Biomedicina / Tesi realitzada a l'Institut de Recerca Biomèdica de Barcelona (IRBB)
openaire +2 more sources
Low/brief glucocorticoid (GC) elevations can enhance mitochondrial output (↑ oxygen consumption rate, OCR; ↑ mitochondrial membrane potential, ΔΨm) and Ca2+ buffering, in part via glucocorticoid receptor (GR) trafficking to mitochondria in complexes with Bcl2 and Bag1.
Paweł Hanus +2 more
wiley +1 more source
Neurodegeneration as a consequence of failed mitochondrial maintenance [PDF]
Maintaining the functional integrity of mitochondria is pivotal for cellular survival. It appears that neuronal homeostasis depends on high-fidelity mitochondria, in particular.
Karbowski, Mariusz, Neutzner, Albert
core
Role of Septin7 in mitochondrial dynamics and oxidative metabolism in C2C12 skeletal muscle cells
Abstract figure legend Knockdown of Septin7 alters the expression of markers responsible for mitochondrial dynamics. Members of the electron transport chain are also affected by diminished Septin7 level resulting in functional changes of mitochondrial respiration. Abstract Mitochondria are dynamic organelles that undergo fusion and fission.
Andrea Telek +13 more
wiley +1 more source
Mitochondrial dysfunction drives intervertebral disc degeneration, and mitochondrial dynamics are regulated by mitofusins (MFNs). In this study, we evaluated the roles of MFN1 and MFN2 in mitochondrial quality control and their responses to inflammation ...
Jae Won Shin +7 more
doaj +1 more source
Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration [PDF]
Research efforts during the last decade have deciphered the basic molecular mechanisms governing mitochondrial fusion and fission. We now know that in mammalian cells mitochondrial fission is mediated by the large GTPase dynamin-related protein 1 (Drp1 ...
Frank, Stephan +3 more
core
Fusion activators enhance mitochondrial function. [PDF]
Rosencrans WM, Chan DC.
europepmc +1 more source
Genetic studies of normal tension glaucoma [PDF]
D.Yu. Plotnikov, E.V. Valeeva Kazan State Medical University, Kazan, Russian Federation The paper presents a review of literature on genetic studies of normal tension glaucoma (NTG).
D.Yu. Plotnikov, E.V. Valeeva
doaj

