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Hypertrophic Cardiomyopathy Through the Lens of Mitochondria. [PDF]

open access: yesBiomedicines
Kirichenko TV   +5 more
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Evaluation of the role of mitofusin‐1 and mitofusin‐2 in periodontal disease

Journal of Periodontology, 2023
AbstractBackgroundMitochondria and endoplasmic reticulum are key cellular organelles and create contact sites (mitochondria‐endoplasmic reticulum contact [MERC]), which plays a major role in calcium metabolism, apoptotic processes, and inflammation.
Ömer Alperen Kırmızıgül   +5 more
openaire   +2 more sources

Conditional deletion of myeloid-specific mitofusin 2 but not mitofusin 1 promotes kidney fibrosis

Kidney International, 2022
Macrophages exert critical functions during kidney injury, inflammation, and tissue repair or fibrosis. Mitochondrial structural and functional aberrations due to an imbalance in mitochondrial fusion/fission processes are implicated in the pathogenesis of chronic kidney disease.
Divya Bhatia   +6 more
openaire   +2 more sources

Targeted Deletion of Mitofusin 1 and Mitofusin 2 Causes Female Infertility and Loss of Follicular Reserve

Reproductive Sciences, 2022
Mitochondria are dynamic organelles that regulate their size, shape, and morphology through mechanisms called fusion and fission, to continually adapt themselves to their bioenergetic environment. These mechanisms play a critical role to maintain the mitochondrial function under metabolic and environmental stress.
Mauro Cozzolino, Yagmur Ergun, Emre Seli
openaire   +2 more sources

Mitofusin 2 Inhibits Mitochondrial Antiviral Signaling

Science Signaling, 2009
A protein that mediates mitochondrial fusion also suppresses innate immune responses to viral infection.
Kai, Yasukawa   +7 more
openaire   +2 more sources

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