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Mitophagy in gastrointestinal tumors: mechanisms and new targets for immunotherapy. [PDF]
Front OncolZhang T +7 more
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Inhibiting HSP27 activates the XBP1s/CerS1 interplay, which triggers DRP1-driven mitophagy, thereby protecting against cell death and promoting the KSHV lytic cycle in primary effusion lymphoma cells. [PDF]
Cell Death DiscovGonnella R +8 more
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The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]
PLoS BiolRestrepo LJ +3 more
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SIRT3 attenuates AGEs-induced senescence in human granulosa cells through enhancing mitophagy. [PDF]
Cell Biol ToxicolLi S +5 more
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Nature Reviews Molecular Cell Biology, 2010 Autophagy not only recycles intracellular components to compensate for nutrient deprivation but also selectively eliminates organelles to regulate their number and maintain quality control. Mitophagy, the specific autophagic elimination of mitochondria, has been identified in yeast, mediated by autophagy-related 32 (Atg32), and in mammals during red ...
Richard J Youle, Derek P Narendra
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2021
Mitochondria play a central role in primary metabolism in plants as well as in heterotrophic eukaryotes. Plants must control the quality and number of mitochondria in response to a changing environment, across cell types and developmental stages. Mitophagy is defined as the degradation of mitochondria by autophagy, an evolutionarily conserved system ...
Sakuya, Nakamura +2 more
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Mitochondria play a central role in primary metabolism in plants as well as in heterotrophic eukaryotes. Plants must control the quality and number of mitochondria in response to a changing environment, across cell types and developmental stages. Mitophagy is defined as the degradation of mitochondria by autophagy, an evolutionarily conserved system ...
Sakuya, Nakamura +2 more
openaire +2 more sources
Yeast mitophagy: Unanswered questions
Biochimica et Biophysica Acta (BBA) - General Subjects, 2021Superfluous and damaged mitochondria need to be efficiently repaired or removed. Mitophagy is a selective type of autophagy that can engulf a portion of mitochondria within a double-membrane structure, called a mitophagosome, and deliver it to the vacuole for degradation. Mitophagy has significant physiological functions from yeast to human, and recent
Yuxiang J, Huang, Daniel J, Klionsky
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The International Journal of Biochemistry & Cell Biology, 2014
Eukaryotes employ elaborate mitochondrial quality control to maintain the function of the power-generating organelle. Mitochondrial quality control is particularly important for the maintenance of neural and muscular tissues. Mitophagy is specialized version of the autophagy pathway. Mitophagy delivers damaged mitochondria to lysosomes for degradation.
Nobutaka, Hattori +2 more
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Eukaryotes employ elaborate mitochondrial quality control to maintain the function of the power-generating organelle. Mitochondrial quality control is particularly important for the maintenance of neural and muscular tissues. Mitophagy is specialized version of the autophagy pathway. Mitophagy delivers damaged mitochondria to lysosomes for degradation.
Nobutaka, Hattori +2 more
openaire +2 more sources