Results 291 to 300 of about 96,831 (392)

Parkin-ACSL4 axis in ferroptosis regulation: a narrative review on therapeutic insights from exercise in aging cardiomyocytes. [PDF]

NPJ Metab Health Dis
Kordi N, Bagherzadeh-Rahmani B, KheirAndish R, Rezaali R, Stockwell BR.   +4 more
europepmc   +1 more source

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, EarlyView.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

Mitochondrial dynamics in cisplatin resistance: molecular mechanisms and therapeutic targeting. [PDF]

Front Oncol
Huang W, Sun W, Yang Z, Li Y, Wang Z.
europepmc   +1 more source

Beyond diabetes and obesity: GLP‐1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani, Carlos A. Mandarim‐de‐Lacerda   +1 more
wiley   +1 more source

Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux. [PDF]

Cell Oncol (Dordr)
Cao X, Li Y, Guo B, Liu Y, Wang B, Wang H, Lu J, Wei L, Gao Y, Guo Y, Wu T.   +10 more
europepmc   +1 more source

Pink1 balances reticulophagy and mitophagy by regulating distinct E3 ubiquitin ligases [PDF]

Zhangyuan Yin, Daniel J. Klionsky
openalex   +1 more source

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson, Yanwei Cai, Ana Gabriela Vasconcelos, Peter Orchard, Paul L. Auer, Guillaume Lettre, Jia Wen, Nora Franceschini, Charles Kooperberg, Wei Sun, Li Hsu, Laura M. Raffield, Alex P. Reiner   +12 more
wiley   +1 more source

CAMK1D activates AMPK/PINK1/Parkin-dependent mitophagy to promote enzalutamide resistance in prostate cancer. [PDF]

Cell Death Dis
Sun F, Qu Y, Mei S, Zhang L, Shao X, Wang X, Liu S, Wang M, Liu W, Yang M, Hu J, Shi B, Gao L, Han B.   +13 more
europepmc   +1 more source

Chlorogenic acid modulates mitochondrial damage and mitophagy to repair injured myocardial tissue and cells [PDF]

Hao Ling, Liang Yu, Chunli Song
openalex   +1 more source