Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]
Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Cross, R. A. +2 more
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In this article, we present the data related to motivational factors given by the medical (n=118) and nursing (n=217) staff, of a Greek Public General Hospital during a period of financial austerity.
Marianna Charalambous +2 more
doaj +1 more source
Chromosome Oscillations in Mitosis [PDF]
Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar +8 more
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Characteristics of mitosis in the gametophyte cells of the marine green alga Monostroma angicava
Background Some marine algae exhibit several characteristics of mitosis (e.g., the timing of mitosis such as diurnal periodicity) that are unique from those of land plants.
Yusuke Horinouchi, Tatsuya Togashi
doaj +1 more source
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Gruneberg, Ulrike +3 more
core +3 more sources
Positive Feedback Keeps Duration of Mitosis Temporally Insulated from Upstream Cell-Cycle Events [PDF]
Cell division is characterized by a sequence of events by which a cell gives rise to two daughter cells. Quantitative measurements of cell-cycle dynamics in single cells showed that despite variability in G1-, S-, and G2 phases, duration of mitosis is ...
Araujo, AR +3 more
core +1 more source
Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. [PDF]
As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis.
Antkowiak, Mark +11 more
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The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear.
Ao Guo +6 more
doaj +1 more source
Exotic mitotic mechanisms [PDF]
The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
core +1 more source
Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
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