Results 21 to 30 of about 309,266 (377)

Single-cell monitoring of dry mass and dry mass density reveals exocytosis of cellular dry contents in mitosis

open access: yeseLife, 2022
Cell mass and composition change with cell cycle progression. Our previous work characterized buoyant mass dynamics in mitosis (Miettinen et al., 2019), but how dry mass and cell composition change in mitosis has remained unclear.
Teemu P Miettinen   +3 more
doaj   +1 more source

PREEParing for Mitosis [PDF]

open access: yesDevelopmental Cell, 2013
Reporting in Developmental Cell, Schlaitz et al. (2013) show that endoplasmic reticulum (ER) membrane exclusion from the mitotic spindle is an active process requiring REEP membrane proteins. REEP protein depletion results in ER membrane retention on the spindle and chromosomes, leading to defects in chromosome segregation and nuclear envelope assembly.
openaire   +3 more sources

Triggering mitosis [PDF]

open access: yesFEBS Letters, 2019
Entry into mitosis is triggered by the activation of cyclin‐dependent kinase 1 (Cdk1). This simple reaction rapidly and irreversibly sets the cell up for division. Even though the core step in triggering mitosis is so simple, the regulation of this cellular switch is highly complex, involving a large number of interconnected signalling cascades.
Adrijana Crncec, Helfrid Hochegger
openaire   +2 more sources

Automated mitosis detection using texture, SIFT features and HMAX biologically inspired approach

open access: yesJournal of Pathology Informatics, 2013
Context: According to Nottingham grading system, mitosis count in breast cancer histopathology is one of three components required for cancer grading and prognosis. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader
Humayun Irshad   +6 more
doaj   +1 more source

Challenging mitosis detection algorithms: Global labels allow centroid localization [PDF]

open access: yesIDEAL 2022, 2022
Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large size of augmented biopsy slides, the low density of mitotic cells, and pattern heterogeneity.
arxiv   +1 more source

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]

open access: yes, 2007
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Thein, Kerstin H.   +3 more
core   +2 more sources

Biophysics of mitosis [PDF]

open access: yesQuarterly Reviews of Biophysics, 2012
AbstractMitosis is the process by which eukaryotic cells organize and segregate their chromosomes in preparation for cell division. It is accomplished by a cellular machine composed largely of microtubules (MTs) and their associated proteins. This article reviews literature on mitosis from a biophysical point of view, drawing attention to the assembly ...
Maxim I. Molodtsov   +2 more
openaire   +3 more sources

Mitosis Methods & Protocols

open access: yesEuropean Journal of Histochemistry, 2010
Mitosis Methods & Protocols Andrew D. McAinsh (Edt) Humana press, Totowa, New Jersey (USA) Series: Springer Protocols Methods in Molecular Biology, Volume 545, 2009 ISBN: 978-1-60327-992-5   It is quite clear from the contents of this book that
CarloAlberto Redi
doaj   +1 more source

Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis [PDF]

open access: yes, 2012
The nucleocytoplasmic partitioning of nanoparticles as a result of cell division is highly relevant to the field of nonviral gene delivery. We reviewed the literature on the intracellular distribution of cell organelles (the endosomal vesicles, Golgi ...
Braeckmans, Kevin   +5 more
core   +1 more source

Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization

open access: yesStem Cell Reports, 2017
The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear.
Ao Guo   +6 more
doaj   +1 more source

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