Results 21 to 30 of about 286,319 (230)
Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]
Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Cross, R. A.+2 more
core +2 more sources
Entry into mitosis is triggered by the activation of cyclin‐dependent kinase 1 (Cdk1). This simple reaction rapidly and irreversibly sets the cell up for division. Even though the core step in triggering mitosis is so simple, the regulation of this cellular switch is highly complex, involving a large number of interconnected signalling cascades.
Adrijana Crncec, Helfrid Hochegger
openaire +2 more sources
Cell mass and composition change with cell cycle progression. Our previous work characterized buoyant mass dynamics in mitosis (Miettinen et al., 2019), but how dry mass and cell composition change in mitosis has remained unclear.
Teemu P Miettinen+3 more
doaj +1 more source
Mitosis Methods & Protocols Andrew D. McAinsh (Edt) Humana press, Totowa, New Jersey (USA) Series: Springer Protocols Methods in Molecular Biology, Volume 545, 2009 ISBN: 978-1-60327-992-5 It is quite clear from the contents of this book that
CarloAlberto Redi
doaj +1 more source
The transformation of a single fertilised egg into an adult human consisting of tens of trillions of highly diverse cell types is a marvel of biology. The expansion is largely achieved by cell duplication through the process of mitosis.
Charlotte Nugues+2 more
doaj +1 more source
Challenging mitosis detection algorithms: Global labels allow centroid localization [PDF]
Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large size of augmented biopsy slides, the low density of mitotic cells, and pattern heterogeneity.
arxiv +1 more source
Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis [PDF]
The nucleocytoplasmic partitioning of nanoparticles as a result of cell division is highly relevant to the field of nonviral gene delivery. We reviewed the literature on the intracellular distribution of cell organelles (the endosomal vesicles, Golgi ...
Braeckmans, Kevin+5 more
core +1 more source
Podocyte Mitosis - A Catastrophe [PDF]
Podocyte loss plays a key role in the progression of glomerular disorders towards glomerulosclerosis and chronic kidney disease. Podocytes form unique cytoplasmic extensions, foot processes, which attach to the outer surface of the glomerular basement membrane and interdigitate with neighboring podocytes to form the slit diaphragm.
LASAGNI, LAURA+4 more
openaire +4 more sources
The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear.
Ao Guo+6 more
doaj +1 more source
Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress [PDF]
The MUS81 complex is crucial for preserving genome stability through the resolution of branched DNA intermediates in mitosis. However, untimely activation of the MUS81 complex in S-phase is dangerous.
Franchitto, Annapaola+11 more
core +1 more source