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Anti-tumor pharmacology of natural products targeting mitosis
Cancer has been an insurmountable problem in the history of medical science. The uncontrollable proliferation of cancer cells is one of cancer’s main characteristics, which is closely associated with abnormal mitosis.
Manru Huang+7 more
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SmallMitosis: Small Size Mitotic Cells Detection in Breast Histopathology Images
Mitotic figure count acts as a proliferative marker to measure aggressiveness of the breast cancer tumor. In this article, we have proposed a novel framework named SmallMitosis to detect mitotic cells particularly very small size mitosis from hematoxylin
Tasleem Kausar+3 more
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In this article, we present the data related to motivational factors given by the medical (n=118) and nursing (n=217) staff, of a Greek Public General Hospital during a period of financial austerity.
Marianna Charalambous+2 more
doaj +1 more source
Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]
Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Cross, R. A.+2 more
core +2 more sources
Hyphal growth of phagocytosed fusarium oxysporum causes cell lysis and death of murine macrophages [PDF]
Peer reviewedPublisher ...
Bain, Judith M+4 more
core +11 more sources
Characteristics of mitosis in the gametophyte cells of the marine green alga Monostroma angicava
Background Some marine algae exhibit several characteristics of mitosis (e.g., the timing of mitosis such as diurnal periodicity) that are unique from those of land plants.
Yusuke Horinouchi, Tatsuya Togashi
doaj +1 more source
Cell volume and dry mass are typically correlated. However, in this issue, Zlotek-Zlotkiewicz et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201505056) and Son et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201505058) use new live-cell techniques to show that entry to mitosis coincides with rapid cell swelling, which is reversed ...
Evgeny Zatulovskiy, Jan M. Skotheim
openaire +3 more sources
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Gruneberg, Ulrike+3 more
core +3 more sources
Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. [PDF]
As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis.
Antkowiak, Mark+11 more
core +2 more sources
The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear.
Ao Guo+6 more
doaj +1 more source