Results 31 to 40 of about 379,827 (391)
The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear.
Ao Guo+6 more
doaj +1 more source
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Gruneberg, Ulrike+3 more
core +3 more sources
Automated mitosis detection using texture, SIFT features and HMAX biologically inspired approach
Context: According to Nottingham grading system, mitosis count in breast cancer histopathology is one of three components required for cancer grading and prognosis. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader
Humayun Irshad+6 more
doaj +1 more source
Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis [PDF]
The nucleocytoplasmic partitioning of nanoparticles as a result of cell division is highly relevant to the field of nonviral gene delivery. We reviewed the literature on the intracellular distribution of cell organelles (the endosomal vesicles, Golgi ...
Braeckmans, Kevin+5 more
core +1 more source
Mitosis Methods & Protocols Andrew D. McAinsh (Edt) Humana press, Totowa, New Jersey (USA) Series: Springer Protocols Methods in Molecular Biology, Volume 545, 2009 ISBN: 978-1-60327-992-5 It is quite clear from the contents of this book that
CarloAlberto Redi
doaj +1 more source
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest [PDF]
Oncogene-induced senescence (OIS) is a tumor suppression mechanism that blocks cell proliferation in response to oncogenic signaling. OIS is frequently accompanied by multinucleation; however, the origin of this is unknown.
Adams, Peter D.+20 more
core +2 more sources
Aurora-PLK1 cascades as key signaling modules in the regulation of mitosis
Precise spatiotemporal control enables the mitotic kinases Aurora and PLK1 to orchestrate distinct mitotic processes. Gloss Ever since its first observation under the microscope over a century ago, mitosis—the process wherein a cell divides into two ...
V. Joukov, A. De Nicolo
semanticscholar +1 more source
Podocyte Mitosis - A Catastrophe [PDF]
Podocyte loss plays a key role in the progression of glomerular disorders towards glomerulosclerosis and chronic kidney disease. Podocytes form unique cytoplasmic extensions, foot processes, which attach to the outer surface of the glomerular basement membrane and interdigitate with neighboring podocytes to form the slit diaphragm.
LASAGNI, LAURA+4 more
openaire +4 more sources
Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry. [PDF]
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Baum, B+3 more
core +1 more source
AbstractMitosis is the process by which eukaryotic cells organize and segregate their chromosomes in preparation for cell division. It is accomplished by a cellular machine composed largely of microtubules (MTs) and their associated proteins. This article reviews literature on mitosis from a biophysical point of view, drawing attention to the assembly ...
Maxim I. Molodtsov+2 more
openaire +3 more sources