Automated mitosis detection using texture, SIFT features and HMAX biologically inspired approach
Context: According to Nottingham grading system, mitosis count in breast cancer histopathology is one of three components required for cancer grading and prognosis. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader
Humayun Irshad+6 more
doaj +1 more source
Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates. [PDF]
As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis.
Antkowiak, Mark+11 more
core +2 more sources
Chromosome condensation in mitosis and meiosis of rye (Secale cereale L.) [PDF]
Structural investigation and morphometry of meiotic chromosomes by scanning electron microscopy (in comparison to light microscopy) of all stages of condensation of meiosis I + II show remarkable differences during chromosome condensation in mitosis and ...
Herrmann, Reinhold G.+2 more
core +1 more source
Context: According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations.
Humayun Irshad
doaj +1 more source
Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry. [PDF]
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Baum, B+3 more
core +1 more source
Detection of mitotic tumor cells per tissue area is one of the critical markers of breast cancer prognosis. The aim of this paper is to develop a method for the automatic detection of mitotic figures from breast cancer histological slides using a ...
Meriem Sebai+2 more
doaj +1 more source
Mitosis Detection from Partial Annotation by Dataset Generation via Frame-Order Flipping [PDF]
Detection of mitosis events plays an important role in biomedical research. Deep-learning-based mitosis detection methods have achieved outstanding performance with a certain amount of labeled data. However, these methods require annotations for each imaging condition. Collecting labeled data involves time-consuming human labor.
arxiv
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest [PDF]
Oncogene-induced senescence (OIS) is a tumor suppression mechanism that blocks cell proliferation in response to oncogenic signaling. OIS is frequently accompanied by multinucleation; however, the origin of this is unknown.
Adams, Peter D.+20 more
core +2 more sources
Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis [PDF]
Sds22 defines protein phosphatase 1 location and function at kinetochores and subsequent activity of aurora B in ...
DeLuca, Jennifer G.+5 more
core +3 more sources
Computer-Aided Assessment of Melanocytic Lesions by Means of a Mitosis Algorithm
An increasing number of pathology laboratories are now fully digitised, using whole slide imaging (WSI) for routine diagnostics. WSI paves the road to use artificial intelligence (AI) that will play an increasing role in computer-aided diagnosis (CAD ...
Bart Sturm+9 more
doaj +1 more source