Results 31 to 40 of about 379,827 (391)

Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization

open access: yesStem Cell Reports, 2017
The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear.
Ao Guo   +6 more
doaj   +1 more source

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]

open access: yes, 2007
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Gruneberg, Ulrike   +3 more
core   +3 more sources

Automated mitosis detection using texture, SIFT features and HMAX biologically inspired approach

open access: yesJournal of Pathology Informatics, 2013
Context: According to Nottingham grading system, mitosis count in breast cancer histopathology is one of three components required for cancer grading and prognosis. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader
Humayun Irshad   +6 more
doaj   +1 more source

Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis [PDF]

open access: yes, 2012
The nucleocytoplasmic partitioning of nanoparticles as a result of cell division is highly relevant to the field of nonviral gene delivery. We reviewed the literature on the intracellular distribution of cell organelles (the endosomal vesicles, Golgi ...
Braeckmans, Kevin   +5 more
core   +1 more source

Mitosis Methods & Protocols

open access: yesEuropean Journal of Histochemistry, 2010
Mitosis Methods & Protocols Andrew D. McAinsh (Edt) Humana press, Totowa, New Jersey (USA) Series: Springer Protocols Methods in Molecular Biology, Volume 545, 2009 ISBN: 978-1-60327-992-5   It is quite clear from the contents of this book that
CarloAlberto Redi
doaj   +1 more source

Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest [PDF]

open access: yes, 2015
Oncogene-induced senescence (OIS) is a tumor suppression mechanism that blocks cell proliferation in response to oncogenic signaling. OIS is frequently accompanied by multinucleation; however, the origin of this is unknown.
Adams, Peter D.   +20 more
core   +2 more sources

Aurora-PLK1 cascades as key signaling modules in the regulation of mitosis

open access: yesScience Signaling, 2018
Precise spatiotemporal control enables the mitotic kinases Aurora and PLK1 to orchestrate distinct mitotic processes. Gloss Ever since its first observation under the microscope over a century ago, mitosis—the process wherein a cell divides into two ...
V. Joukov, A. De Nicolo
semanticscholar   +1 more source

Podocyte Mitosis - A Catastrophe [PDF]

open access: yesCurrent Molecular Medicine, 2012
Podocyte loss plays a key role in the progression of glomerular disorders towards glomerulosclerosis and chronic kidney disease. Podocytes form unique cytoplasmic extensions, foot processes, which attach to the outer surface of the glomerular basement membrane and interdigitate with neighboring podocytes to form the slit diaphragm.
LASAGNI, LAURA   +4 more
openaire   +4 more sources

Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry. [PDF]

open access: yes, 2015
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Baum, B   +3 more
core   +1 more source

Biophysics of mitosis [PDF]

open access: yesQuarterly Reviews of Biophysics, 2012
AbstractMitosis is the process by which eukaryotic cells organize and segregate their chromosomes in preparation for cell division. It is accomplished by a cellular machine composed largely of microtubules (MTs) and their associated proteins. This article reviews literature on mitosis from a biophysical point of view, drawing attention to the assembly ...
Maxim I. Molodtsov   +2 more
openaire   +3 more sources

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