Results 51 to 60 of about 91,818 (255)
CYTOLOGICAL EFFECT OF GAMMA IRRADIATION ON MITOTIC ACTIVITY ON VICIA FABA PLANTS. [PDF]
Journal of Plant Production, 2000 The present study was carried to investigate the cytological effects of six doses of gamma rays (1,2,3,4,5 K.rad and fractionated does (1 K.rad/24hrs for 5 days) in root meristems of Vicia faba plant.
Asmahan Mahmoud
doaj +1 more source
Risk factors for positive sentinel lymph nodes in head and neck melanoma — a survival analysis
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: Sentinel lymph node biopsy is the gold standard procedure for head and neck cutaneous melanoma staging. Objective: To evaluate the technical aspects, positivity and prognostic effect of the cervico-facial sentinel lymph node biopsy. Methods:
Neide Lira Bonachela +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The Iraqi Journal of Agricultural science, 2020 This study was aimed to investigate cytogenetic effects of the crude saponinsof Yucca elephantipes leaves on mitosis. The root tips of Allium cepa L. were used as plant test system in vivo. Root tips of A.
Mohammed & Najem
doaj +1 more source
The Effects of Zinc Phosphide and Brodifacoum on Mitotic Index and Chromosomal Aberrations in Germ Cells of Wild type and Laboratory Mice (Mus Musculus) [PDF]
Engineering and Technology Journal, 2014 The genotoxic effects of two wildy used rodenticides in Iraq (Zinc phosphide and Brodifacoum) were studied in wildtype and Balbc mice,by using mitotic index(MI) and chromosomal aberration (CA).
Abbas Abdullah Mohammed, Smail K.Subber
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Sensitivity of vegetables seeds in the assessment of water quality in bioassays [PDF]
Biotemas, 2012 Since seeds tolerate sress levels and their vital functions are correlated to the environment, the study aimed to evaluate lettuce and onions as bioindicators to test water quality, and the parameters to assess water quality vary according to the seasons
Antônio Lucio Melo Martins +3 more
doaj
Role of Ki-67 as a prognostic factor in gastrointestinal stromal tumors
, 2013 AIM: To investigate primarily the prognostic value of Ki-67, as well as other parameters, in gastrointestinal stromal tumors (GISTs). ----- METHODS: Ki-67, c-KIT, platelet-derived growth factor receptor-alpha (PDGFRα), smooth muscle actin (SMA ...
Alerić, Ivan +8 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source