Results 151 to 160 of about 327,045 (196)
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Molecular components of the mitotic spindle
BioEssays, 1992AbstractMitotic spindles constitute the machinery responsible for equidistribution of the genetic material into each daughter cell during cell division. They are transient and hence quite labile structures, changing their morphology even while performing their function. Biochemical, immunological and genetic analyses of mitotic cells have allowed us to
R, Kuriyama, C, Nislow
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1984
Publisher Summary This chapter focuses on one aspect of the biochemistry of mitotic spindles—the presence of adenosine triphosphate (ATP) hydrolyzing enzymes. ATPase in the mitotic spindle is discussed. There is a physiological evidence for dynein ATPase in mitotic spindles.
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Publisher Summary This chapter focuses on one aspect of the biochemistry of mitotic spindles—the presence of adenosine triphosphate (ATP) hydrolyzing enzymes. ATPase in the mitotic spindle is discussed. There is a physiological evidence for dynein ATPase in mitotic spindles.
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Biochemistry of the Mitotic Spindle
1979Publisher Summary The mitotic spindle consists of the chromatic and the achromatic figure. The chromatic figure consists of the chromosomes and includes their attachment points to the spindle, the kinetochores. The achromatic figure is more difficult to define.
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Mescaline as a mitotic spindle inhibitor
Nature, 1976COLCHICINE and its methyl derivative colcemid not only inhibit microtubule self-assembly1 but also affect fast transport in nerve2. A report that mescaline likewise inhibits the rapid component of axoplasmic transport in nerve3, led us to investigate the effects of this drug on mitosis, and on purified microtubule protein (tubulin4).
C M, Harrisson, B M, Page, H M, Keir
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The Evolution of the Mitotic Spindle
1976Publisher Summary This chapter discusses the evolution of the mitotic spindle. The recounting of the evolutionary past of the mitotic processes of chromosome movement would entail tracing a gradual shift from membranes to micros as the primary producer of forces for chromosome movement.
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Control of Mitotic Spindle Length
Annual Review of Cell and Developmental Biology, 2010The mitotic spindle accurately segregates genetic instructions by moving chromosomes to spindle poles (anaphase A) and separating the poles (anaphase B) so that, in general, the chromosomes and poles are positioned near the centers of the nascent daughter cell products of each cell division.
Gohta, Goshima, Jonathan M, Scholey
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Mitotic Spindle Assembly In Vitro
Current Protocols in Cell Biology, 2001AbstractThe protocols in this unit describe the preparation of materials for an in vitro assay of mitotic spindle assembly in Xenopus egg extracts. Fluorochrome‐labeled tubulin is used to visualize microtubule asters and spindles.
J, Merlie, R, Heald
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Mitotic spindle pole separation
Trends in Cell Biology, 1993Eukaryotic cells utilize a microtubular spindle to segregate chromosomes during mitosis. Chromosome segregation requires the timely separation of the mitotic spindle poles to which the chromosomes are attached. Recent studies at the molecular and cellular levels have provided new insights into the mechanism and regulation of this process.
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Mitotic spindle: Focus on the function of huntingtin
The International Journal of Biochemistry & Cell Biology, 2011Mitotic spindle assembly and orientation are tightly regulated to allow the appropriate segregation of genetic material and cell fate determinants during symmetric and asymmetric divisions. Microtubules and many proteins including the dynein/dynactin complex and the large nuclear mitotic apparatus NuMA protein, are fundamental players in these ...
Godin, Juliette, Humbert, Sandrine
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Polarity of microtubules of the mitotic spindle
Journal of Molecular Biology, 1978Abstract Microtubules are polar structures that grow preferentially at one end. Measurement of their rate of directional growth can be used as a polarity indicator to determine their orientation with respect to a nucleation site. The results are interpreted to signify that the microtubules originating from the centrosomes and chromosomes of the ...
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