Results 151 to 160 of about 130,672 (286)

Plaque‐type trichoblastoma and its siblings: A (follicular tumour) family history

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ines Bertlich   +4 more
wiley   +1 more source

A Case of Pediatric Spitz Melanoma With a ZEB2::ALK Fusion

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT We present a rare case of Spitz melanoma in a 3‐year‐old male patient with a ZEB2::ALK fusion. This ALK‐fused tumor exhibited aggressive behavior, recurring after an initial wide local excision and progressing despite neoadjuvant immunotherapy with a PD‐1 inhibitor.
Nathanael C. Jensen   +3 more
wiley   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye   +5 more
wiley   +1 more source

Kinetochore size correlates with chromosome size in Star of Bethlehem (Ornithogalum kochii Parl., Asparagaceae)

open access: yesPlant Biology, EarlyView.
Cytogenetic quantification of KNL1‐labelled kinetochores in Ornithogalum kochii reveals a significant positive scaling relationship between chromosome size and kinetochore size, demonstrating that chromosome–kinetochore scaling operates even across moderate intra‐karyotype size variation.
K. Panda, M. Hroneš, F. Zedek
wiley   +1 more source

DYN-1 regulates SPD-2 and PLK-1 localization and mitotic spindle pole organization. [PDF]

open access: yesMol Biol Cell
Dierlam C   +5 more
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri   +13 more
wiley   +1 more source

Reversible arginine methylation of PI3KC2α controls mitotic spindle dynamics. [PDF]

open access: yesCell Commun Signal
Cho Y   +6 more
europepmc   +1 more source

On the assembly of the mitotic spindle, bistability and hysteresis. [PDF]

open access: yesCell Mol Life Sci, 2023
Serpico AF, Pisauro C, Grieco D.
europepmc   +1 more source

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation. [PDF]

open access: yesCell Mol Life Sci, 2023
Faienza F   +21 more
europepmc   +1 more source

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour   +6 more
wiley   +1 more source

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