Results 131 to 140 of about 130,672 (286)

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, EarlyView.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

Diagnostic and therapeutic approaches of para‐testicular SCRMS in an adolescent patient: A case report

UroPrecision, EarlyView.
Abstract Background Para‐testicular rhabdomyosarcoma (RMS) is a rare and aggressive malignancy primarily affecting children and adolescents, with peak incidence between ages 2 and 5 years. Of the histological variants of RMS, the spindle cell type of RMS is particularly uncommon, accounting for approximately 5% of cases.
Kholoud Alabassi, Yaser M. Ata, Khaled Murshed, Ibrahim A. Khalil, Noheir M. Taha, Khalid Al Rumaihi   +5 more
wiley   +1 more source

Prostatic stromal tumors with uncertain malignant potential: A scoping review of clinical challenges and management strategies

UroPrecision, EarlyView.
Abstract Prostatic stromal tumor of uncertain malignant potential (STUMP) is a rare neoplasm arising from specialized prostatic stromal cells with a broad range of histologic patterns and unpredictable clinical behavior. It is often challenging to distinguish STUMP from prostatic stromal sarcoma due to morphological similarities, necessitating specific
Ibrahim A. Khalil, Abdullah M. Al‐Jubouri, Khaled Murshed, Ahmad R. Al‐Qudimat, Majd Alkabbani, Nagy Younes, Khalid Al Jalham, Khalid Al Rumaihi   +7 more
wiley   +1 more source

Molecular and Cell Biological Characterization of Patient‐Derived Head and Neck Squamous Carcinoma Cell Lines

Cancer Science, EarlyView.
Patient‐derived head and neck squamous cell carcinoma (HNSCC) cells were genomically and cytogenetically characterized, revealing actionable alterations and chromosomal instability. Targeted therapies suppressed growth according to EGFR amplification or PIK3CA mutation status.
Kazue Ito, Noriko Ishida, Shin Ito, Norihisa Shindo, Satoshi Souma, Mai Mochizuki, Haruna Fujimori, Keiichi Tamai, Takayuki Imai, Tomoko Yamazaki, Kazunori Yamaguchi, Kento Sasaki, Yuya Miyakura, Shigekazu Murakami, Yuka Unno, Naoki Asano, Yukinori Asada, Jun Yasuda   +17 more
wiley   +1 more source

Nodules in an Infant's Fingers

JEADV Clinical Practice, EarlyView.
Adnan Ahmad, Mariam Alshammari, Alsadat Mosbeh, Abeer Albazali, Kawthar Safar, Fatmah Al‐Sughayer   +5 more
wiley   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

Cell Proliferation, EarlyView.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao, Yuqing Sun, Yutao Huang, Qinghang Meng, Xinhua Lin, Wei Wei, Xiaofang Tang   +6 more
wiley   +1 more source

Desmoplastic Cutaneous Squamous Cell Carcinoma Is an Aggressive and Potentially Fatal Skin Cancer: A Systematic Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT The incidence and mortality of cutaneous squamous cell carcinoma (cSCC) are increasing. Desmoplastic cSCC (dcSCC) is an uncommon yet highly aggressive variant which has received relatively little attention in the literature. No systematic reviews of dcSCC are currently available.
Andrew Dettrick, Haris Mohammed, Thomas Hardman, Nicole Buddle, Ryan Livingston, Duncan Lambie, Rebecca Donkin   +6 more
wiley   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source