Results 121 to 130 of about 198,084 (294)

Piezosurgical partial ostectomy of the incisive bone for an ossifying fibroma removal in a 4‐year‐old Warmblood gelding

Equine Veterinary Journal, EarlyView.
Abstract Background Ossifying fibromas are uncommon in horses and complete surgical excision with premaxillectomy, maxillectomy or mandibulectomy is recommended. Piezosurgery has been previously used in equines only in one study. Objective To report a case of ossifying fibroma treated with piezosurgery and to describe its follow‐up.
G. Forni, M. E. Falomo, I. Casalini, M. Isola   +3 more
wiley   +1 more source

Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint

Cells, 2015
The segregation of the chromosomes during mitosis is an important process, in which the replicated DNA content is properly allocated into two daughter cells.
Ikram Mossaid, Birthe Fahrenkrog
doaj   +1 more source

Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]

, 2007
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Erich A. Nigg, Kleylein-Sohn, J, Nigg, EA, Thein, Kerstin H., Kerstin H. Thein, Gruneberg, Ulrike, Nigg, E. A., Grueneberg, U., Julia Kleylein-Sohn, Thein, KH, Kleylein-Sohn, Julia, Kleylein-Sohn, J., Ulrike Gruneberg, Nigg, Erich A., Thein, K. H.   +14 more
core   +1 more source

Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression

iScience, 2019
Summary: Cytoskeletal cross talk between actin filaments and microtubules is a common mechanism governing the assembly of cellular structures, i.e., during filopodia formation or cilia organization.
Matthias Plessner, Julian Knerr, Robert Grosse   +2 more
doaj   +1 more source

KIF14 and citron kinase act together to promote efficient cytokinesis [PDF]

, 2006
Multiple mitotic kinesins and microtubule-associated proteins (MAPs) act in concert to direct cytokinesis (Glotzer, M. 2005. Science. 307:1735-1739). In anaphase cells, many of these proteins associate with an antiparallel array of microtubules termed ...
Erich A. Nigg, Chan, E. H. Y., Francis A. Barr, Eunice H.Y. Chan, Neef, Rüdiger, Nigg, EA, Xiuling Li, Rüdiger Neef, Gruneberg, Ulrike, Nigg, E. A., Gruneberg, U, Chan, EH, Chalamalasetty, R. B., Nigg, Erich A., Chalamalasetty, Ravindra B., Neef, R, Grüneberg, U., Chalamalasetty, RB, Barr, Francis A., Barr, FA, Li, Xiuling, Ravindra B. Chalamalasetty, Neef, R., Barr, F. A., Chan, Eunice H. Y., Ulrike Gruneberg, Li, X, Li, X. L.   +27 more
core   +1 more source

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, EarlyView.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy

Haematologica, 2013
Spindle poison-based therapy is of only limited benefit in acute myeloid leukemia while lymphoblastic leukemia/lymphoma responds well. In this study, we demonstrated that the spindle assembly checkpoint protein BubR1 was down-regulated in the vast ...
Dominik Schnerch, Andrea Schmidts, Marie Follo, Josefina Udi, Julia Felthaus, Dietmar Pfeifer, Monika Engelhardt, Ralph Wäsch   +7 more
doaj   +1 more source

Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae [PDF]

, 2014
The chromosomal passenger complex (CPC) is a key regulator of eukaryotic cell division, consisting of the protein kinase Aurora B/Ipl1 in association with its activator (INCENP/Sli15) and two additional proteins (Survivin/Bir1 and Borealin/Nbl1). Here we
David A Robinson, Robinson, David A., Corbishley, Stephen, Stark, Michael J. R., Vasso Makrantoni, Michael J R Stark, Makrantoni Vasso, Najma Rachidi, Morrice Nicholas A., Robinson David A., Corbishley Stephen J., Makrantoni, Vasso, Stephen J Corbishley, Stark Michael J. R., Nicholas A Morrice, Rachidi, Najma, Morrice, Nicholas A., Rachidi Najma   +17 more
core   +1 more source

A case report of non‐syndromic colonic ganglioneuroma in a patient with juvenile polyposis

JPGN Reports, EarlyView.
Abstract Colonic ganglioneuromas in children are rare, particularly without associated hereditary syndromes like multiple endocrine neoplasia (MEN2B), neurofibromatosis type 1(NF1), or Phosphatase and tensin homolog hamartoma tumor syndrome (PHTS). We report a 12‐year‐old male with a history of juvenile polyposis syndrome (JPS) and segmental colonic ...
Holly Coffey, Kshitij Arora, Matthew J. Giefer   +2 more
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source