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Mitotic spindle orientation and dynamics are fine-tuned by anisotropic tension via NuMA localisation
Tarannum N +5 more
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Conduction and validation of a novel mitotic spindle assembly related signature in hepatocellular carcinoma: prognostic prediction, tumor immune microenvironment and drug susceptibility. [PDF]
Front GenetZhang Z +5 more
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Mitotic spindle assembly in animal cells: a fine balancing act
Nature Reviews Molecular Cell Biology, 2017SUZANNA Prosser +2 more
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GENETIC ANALYSIS OF THE MITOTIC SPINDLE
Annual Review of Genetics, 1996▪ Abstract Much of our understanding of the molecular basis of mitotic spindle function has been achieved within the past decade. Studies utilizing genetically tractable organisms have made important contributions to this field and these studies form the basis of this review.
M A Hoyt, M Andrew Hoyt
exaly +3 more sources
Centrosomes in mitotic spindle assembly and orientation.
Current Opinion in Structural Biology, 2020The centrosome is present in most animal cells and functions as the major microtubule-organizing center to ensure faithful chromosome segregation during cell division.
I. Hoffmann
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American Journal of Physiology-Cell Physiology, 2000
Subconfluent cultures of Madin-Darby canine kidney (MDCK) and CV-1 cells were immunostained with two monoclonal antibodies (MAbs), MAb X-22 and MAb 23, against clathrin heavy chain and with polyclonal antiserum against a conserved region of all mammalian clathrin light chains.
C T, Okamoto, J, McKinney, Y Y, Jeng
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Subconfluent cultures of Madin-Darby canine kidney (MDCK) and CV-1 cells were immunostained with two monoclonal antibodies (MAbs), MAb X-22 and MAb 23, against clathrin heavy chain and with polyclonal antiserum against a conserved region of all mammalian clathrin light chains.
C T, Okamoto, J, McKinney, Y Y, Jeng
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Theory of Mitotic Spindle Oscillations
Physical Review Letters, 2005During unequal cell division the mitotic spindle is positioned away from the center of the cell before cell cleavage. In many biological systems this repositioning is accompanied by oscillatory movements of the spindle. We present a theoretical description for mitotic spindle oscillations.
Grill, S., Kruse, K., Jülicher, F.
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2012
The mitotic spindle, due to its striking form, has been imaged for well over 100 years. Composed largely of microtubules and chromosomes, the spindle also contains numerous proteins whose roles include biochemical and biophysical regulation of mitosis.
Paul S, Maddox +6 more
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The mitotic spindle, due to its striking form, has been imaged for well over 100 years. Composed largely of microtubules and chromosomes, the spindle also contains numerous proteins whose roles include biochemical and biophysical regulation of mitosis.
Paul S, Maddox +6 more
openaire +2 more sources
Nature, 1971
I PREVIOUSLY suggested that the shape of the metaphase spindle cannot be maintained if there is tension in the component microtubules1. Spindle tension has been detected2,3 and could be due to some other component pulling the chromosomes over the rigid microtubular framework.
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I PREVIOUSLY suggested that the shape of the metaphase spindle cannot be maintained if there is tension in the component microtubules1. Spindle tension has been detected2,3 and could be due to some other component pulling the chromosomes over the rigid microtubular framework.
openaire +2 more sources