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The regulation of mitotic spindle function
Biochemistry and Cell Biology, 1988The process of mitosis includes a series of morphological changes in the cell in which the directional movements of chromosomes are the most prominent. The presence of a microtubular array, known as the spindle or mitotic apparatus, provides at least a scaffold upon which these movements take place.
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Mitotic Spindle Dynamics in Drosophila
2007Mitosis, the process by which the replicated chromosomes are segregated equally into daughter cells, has been studied for over a century. Drosophila melanogaster is an ideal organism for this research. Drosophila embryos are well suited to image mitosis, because during cycles 10-13 nuclei divide rapidly at the surface of the embryo, but mitotic cells ...
Ingrid, Brust-Mascher +1 more
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Mechanobiology of the Mitotic Spindle
Developmental cell, 2021The mitotic spindle is a microtubule-based assembly that separates the chromosomes during cell division. As the spindle is basically a mechanical micro machine, the understanding of its functioning is constantly motivating the development of experimental approaches based on mechanical perturbations, which are complementary to and work together with the
Pavin, Nenad, Tolić, Iva Marija
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Oxidative stress induces mitotic arrest by inhibiting Aurora A‐involved mitotic spindle formation
Free Radical Biology & Medicine, 2017Guang-Fei Wang +6 more
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Control of apoptosis and mitotic spindle checkpoint by survivin
Nature, 1998Fengzhi Li +6 more
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Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 2015Marina Vietri +9 more
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Mitotic spindle multipolarity without centrosome amplification
Nature Cell Biology, 2014H. Maiato, E. Logarinho
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Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
Science, 1999T. Mayer +5 more
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