Results 1 to 10 of about 233,802 (191)

The Role of MMP-9 and MMP-9 Inhibition in Different Types of Thyroid Carcinoma

open access: yesMolecules, 2023
Matrix metalloproteinase-9 (MMP-9), one of the most investigated and studied biomarkers of the MMPs family, is a zinc-dependent proteolytic metalloenzyme whose primary function is degrading the extracellular matrix (ECM).
Zhenshengnan Li   +6 more
doaj   +3 more sources

Comparative Analysis of Blood MMP-9 Concentration in Alcohol- and Opioid-Addicted Patients [PDF]

open access: yesDiseases
Background/Objectives: In brain physiology and disease, MMP-9 is a significant and apparently peculiar factor. Numerous studies have implicated neuroinflammatory processes involving MMP-9 in the pathophysiology of addiction.
Tamar Kartvelishvili   +6 more
doaj   +2 more sources

Does the functional polymorphism-1562C/T of MMP-9 gene influence brain disorders?

open access: yesFrontiers in Cellular Neuroscience, 2023
Metalloproteinase-9 (MMP-9) is one of the most strongly expressed matrix metalloproteinases (MMPs) in the brain. The MMP-9 activity in the brain is strictly regulated, and any disruptions in this regulation contribute to a development of many disorders ...
Sylwia Pabian-Jewuła, Marcin Rylski
doaj   +1 more source

Detection and activity of MMP-2 and MMP-9 in Leishmania amazonensis and Leishmania braziliensis promastigotes

open access: yesBMC Microbiology, 2023
Metalloproteinases (MMPs) are remarkable zinc-dependent endopeptidases, critical for degrading components of the extracellular matrix, thus actively influencing cell migration.
Brenda Furtado Costa   +6 more
doaj   +1 more source

Immunohistochemical characteristics of MMP-9 and TIMP-1 markers expression in the cerebral cortex in diabetes mellitus type 2

open access: yesZaporožskij Medicinskij Žurnal, 2020
Aim – to study the features of immunohistochemical expression of MMP-9, TIMP-1, MMP/TIMP ratio in the cerebral cortex in diabetes mellitus type 2. Materials and methods.
V. O. Shavrin , Yu. M. Avramenko
doaj   +1 more source

Localization Of MMP-2 And MMP-9 In Canine Mammary Gland During Pregnancy [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2014
The mammary gland is unique in its development because most of its branching occurs in adolescent rather than in prenatal development. During early pregnancy extensive ductal side branching occurs while during the second half, secretory lobuloalveolar ...
Despina Pupaki   +3 more
doaj   +3 more sources

Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor [PDF]

open access: yes, 2012
Background: Matrix metalloproteinases (MMPs) are involved in remodeling of the extracellular matrix (ECM) during pregnancy and parturition. Aberrant ECM degradation by MMPs or an imbalance between MMPs and their tissue inhibitors (TIMPs) have been ...
Holtappels, Gabriële   +7 more
core   +8 more sources

Changes of Serum Concentrations of Alkaline Phosphatase and Metalloproteinase-9 in an Ovariectomized Wistar Rat Model of Osteoporosis [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2017
Osteoporosis is a systemic skeletal disease characterized by decreased bone mass, destruction of the microarchitectonics of bone structure and a high risk for fracture. One of the criteria for altered bone homeostasis includes the changes in serum levels
Alexander Blagev   +5 more
doaj   +3 more sources

Effect of Qingguangan on the expressions of MMP-2 and MMP-9 in filtering bleb after trabeculectomy in rabbits

open access: yesInternational Journal of Ophthalmology, 2012
AIM: To explore the effect of Qingguangan on the expressions of MMP-2 and MMP-9 in filtering bleb scarring area after trabeculectomy in rabbit model.METHODS: Thirty-two New Zealand rabbits were randomized into four groups: control group, experimental ...
Wen-Juan Li   +3 more
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

open access: yes, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila   +6 more
core   +2 more sources

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