Results 291 to 300 of about 390,769 (349)

Extracorporeal Shock Wave Therapy in Knee Osteoarthritis: A Mechanistic Narrative Review of Neurogenic Inflammation and the MMP/ADAMTS Axis. [PDF]

Int J Gen Med
Guo Z, Yuan Y, Su H, Dong J.
europepmc   +1 more source

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Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade

Critical Reviews in Biochemistry and Molecular Biology, 2013
Jennifer Vandooren, Philippe E Van den Steen, Ghislain Opdenakker   +2 more
exaly   +2 more sources

Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma

Virchows Archiv, 2009
Merkel cell carcinoma (MCC) is an aggressive cutaneous tumor with poor outcome and increasing incidence. We examined by immunohistochemistry the expression of three novel matrix metalloproteinases (MMPs)-MMP-21, MMP-26, and MMP-28-in 44 primary MCC tumors and six lymph node metastases while MMP-10 served as a positive control. Their mRNA expression was
Sari, Suomela, Virve, Koljonen, Tiina, Skoog, Heli, Kukko, Tom, Böhling, Ulpu, Saarialho-Kere   +5 more
openaire   +2 more sources

Matrix Metalloproteinase (MMP)-7 Activates MMP-8 But Not MMP-13

Medicinal Chemistry, 2006
Matrix Metalloproteinases (MMPs) are a class of zinc-dependent enzymes that degrade extracellular matrix components, particularly collagen. MMPs have been implicated in a diverse list of pathological processes, including cancer and cardiovascular disease.
S, Dozier, G P, Escobar, M L, Lindsey
openaire   +2 more sources

MMP-Responsive 'Smart' Drug Delivery and Tumor Targeting.

TIPS - Trends in Pharmacological Sciences, 2018
Matrix metalloproteinases (MMPs) are major extracellular enzymes involved in cancer initiation, progression, and metastasis. MMPs are widely used as cancer biomarkers and therapeutic targets.
Qing Yao, Long-Fa Kou, Ying Tu, Lin Zhu
semanticscholar   +1 more source

Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis

Scandinavian Journal of Gastroenterology, 2010
Matrix metalloproteinases (MMPs) are considered the predominant proteases in the pathogenesis of mucosal ulcerations associated with inflammatory bowel disease (IBD). Whether the malignancy associated MMP-7 and MMP-13 or the recently cloned MMP-28 convey a certain meaning for intestinal homeostasis and pathogenesis of IBD is currently unknown.
Timo, Rath, Martin, Roderfeld, Jörg Michael, Halwe, Annette, Tschuschner, Elke, Roeb, Jürgen, Graf   +5 more
openaire   +2 more sources

Genes expression of metalloproteinases (MMP-1, MMP-2, MMP-9, and MMP-12) associated with psoriasis

Russian Journal of Genetics, 2011
Using real-time polymerase chain reaction (RT-PCR), we measured mRNA amounts of matrix metalloproteinases (MMPs): MMP-1, MMP-2, MMP-9, and MMP-12 genes in psoriatic lesions and unaffected skin of the same patients. We observed significant (about 15-fold) increase in the expression level of matrix metalloproteinase MMP-1 and MMP-12 genes associated with
N. L. Starodubtseva, V. V. Sobolev, A. G. Soboleva, A. A. Nikolaev, S. A. Bruskin   +4 more
openaire   +1 more source

The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.

Matrix Biology, 2017
This review focuses on the complementary roles of MMP-2 and MMP-9 in leukocyte migration into the brain in neuroinflammation, studied mainly in a murine model of experimental autoimmune encephalomyelitis (EAE) that has similarity to the human disease ...
Melanie-Jane Hannocks, Xueli Zhang, Hanna Gerwien, A. Chashchina, Miriam Burmeister, É. Korpos, Jian Song, Lydia Sorokin   +7 more
semanticscholar   +1 more source