Results 171 to 180 of about 3,785,189 (191)

Epidemiology of Mobile Colistin Resistance Genes Mcr-1 to Mcr-9.

Journal of Antimicrobial Chemotherapy, 2020
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Yang Wang, Jianzhong Shen, Timothy R. Walsh   +2 more
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Mobilized colistin resistance (mcr) genes from 1 to 10: a comprehensive review

Molecular Biology Reports, 2021
At the present time, the polymyxin antibiotic colistin is considered a last-line treatment option for severe human infections caused by multi-drug and carbapenem-resistant Gram-negative bacteria. Lately, the vast spread of colistin resistance among bacteria has got great attention worldwide due to its significant role as the last refuge in treating ...
Nadheema Hammood, Hussein, Israa M S, Al-Kadmy, Butheina Mohammed, Taha, Jumaah Dakel, Hussein   +3 more
openaire   +2 more sources

Global Burden of Colistin Resistant Bacteria: Mobilized Colistin Resistant Genes Study 1980-2018

SSRN Electronic Journal, 2018
Background: Global dissemination of the mobilized colistin resistance (mcr) genes provokes a significant public health threat. However, the exact global prevalence of mcr genes, their reservoirs and the potential transmission pathways to humans have not been comprehensively examined.   Methods: Bilingual publications in four English (PubMed, Scopus,
Mohammed Elbediwi, Yan Li, Narayan Paudyal, Hang Pan, Xiaoliang Li, Shaohua Xie, Andreja Rajkovic, Youjun Feng, Weihuan Fang, Min Yue   +9 more
openaire   +1 more source

Novel Quadruplex PCR for detecting and genotyping mobile colistin resistance genes in human samples

Diagnostic Microbiology and Infectious Disease, 2021
Since 2016, several mobile colistin resistance (mcr) genes have been identified worldwide. It's worth noting that only mcr-1, mcr-3, mcr-8, and mcr-10 have been reported isolated directly from clinical samples which created greater risk to human health than other mcr gene types.
Shuangfang, Hu, Ziquan, Lv, Yang, Wang, Jianzhong, Shen, Yuebin, Ke   +4 more
openaire   +2 more sources

Structural Insights Into the Advancements of Mobile Colistin Resistance Enzymes

Microbiological Research
The plasmid-encoded mobile colistin resistance enzyme (MCR) is challenging the clinical efficacy of colistin as a last-resort antibiotic against multidrug-resistant bacteria. This transferase catalyzes the addition of positively charged phosphoethanolamine to lipid A, and its catalytic domain in the periplasm has been elucidated.
exaly   +3 more sources

Investigation of Mobilized Colistin Resistance Gene-1 in Poultry Pathogenic Escherichia coli

Animal Health Production and Hygiene
This study aimed to determine the presence of mobilized colistin resistance gene 1 (mcr-1), which provides plasmid-mediated colistin resistance in avian pathogenic Escherichia coli (APEC) isolates, and to examine the antibiotic resistance profiles of colistin resistant isolates.
Ecenur Yilmaz, Süheyla Türkyılmaz
openaire   +2 more sources

Structural and functional insight of Mobilized Colistin Resistance-1 variants

Mobilized Colistin Resistance-1 (MCR-1) is a transferase enzyme that confers resistance to polypeptide antimicrobial called colistin (polymyxin E) by modifying lipid A of the Gramnegative bacterial cell membrane. The rapid dissemination of MCR-1 and its variants has become a public health concern. So far, thirty-six variants of MCR-1 have been reported
Tasnimul Arabi Anik, Dipta Chandra Pal, Atiq Abrar Rahman   +2 more
openaire   +1 more source

Bacteria carrying mobile colistin resistance genes and their control measures, an updated review

Archives of Microbiology
The plasmid encoded mobile colistin resistance (MCRs) enzyme poses a significant challenge to the clinical efficacy of colistin, which is frequently employed as a last resort antibiotic for treating infections caused by multidrug resistant bacteria.
openaire   +2 more sources

Detection of Mobile Colistin-Resistance Gene Variants (Mcr-1 and Mcr-2) in Urinary Tract Pathogens in Bangladesh: The Last Resort of Infectious Disease Management Colistin Efficacy Is Under Threat

Expert Review of Clinical Pharmacology, 2021
Adity Rumnaz, Tanjum Ara Haque, Salequl Islam   +2 more
exaly  

Epidemiology and Traits of Mobile Colistin Resistance (Mcr) Gene-Bearing Organisms From Horses

Microorganisms, 2022
James Wabwire Oguttu, Madubuike Umunna Anyanwu, Ishmael Festus Jaja   +2 more
exaly