Results 81 to 90 of about 739,145 (318)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Hardware-in-the-Loop Validation of an FPGA-Based Real-Time Simulator for Power Electronics Applications [PDF]
, 2015 This paper presents the hardware-in-the-loop (HIL) validation of a proposed FPGA-based real-time simulator for power electronics applications. The proposed FPGA-based real-time simulation platform integrates the Modified Nodal Analysis (MNA) method ...
COLAS, Frédéric +5 more
core
On Validating Closed-Loop Behaviour from Noisy Frequency-Response Measurements
, 2005 It is shown how noisy closed-loop frequency-response measurements can be used to obtain pointwise in frequency bounds on the possible difference between the actual closed-loop system and the closed-loop comprising a nominal model of the plant and the ...
Cantoni, M, Date, P
core +1 more source
DesignsGiven the intricate combustion process and the multitude of control parameters inherent to the high-pressure direct injection (HPDI) diesel/natural gas dual-fuel engine, achieving precise combustion control represents a significant challenge.
Xiuyun Shuai +6 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Hopf bifurcation in a gene regulatory network model : molecular movement causes oscillations [PDF]
, 2014 M.A.J.C. and M.S. gratefully acknowledge the support of the ERC Advanced Investigator Grant 227619, “M5CGS — From Mutations to Metastases: Multiscale Mathematical Modelling of Cancer Growth and Spread”. M.S.
Ptashnyk, Mariya +10 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Control Strategy of Hardware-in-the-Loop Simulator EPOS 2.0 for Autonomous Docking Verification
, 2011 This paper briefly describes the hybrid simulator system called European Proximity Operation Simulator (EPOS 2.0) and the development of the hardware-in-the-loop (HIL) docking simulation concept.
Krenn, Rainer +7 more
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Loop Leaping with Closures (proof appendix for conference submission) [PDF]
, 2012 Loop leaping is the colloquial name given to a form of program analysis in which summaries are derived for nested loops starting from the innermost loop and proceeding in a bottom-up fashion considering one more loop at a time.
Brauer, Jorg +3 more
core