Model in the loop - Open Access .click

Results 101 to 110 of about 151,710,486 (253)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero +1 more
wiley +1 more source

Sub-series 2: Publications

, 1983
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core +1 more source

Sub-series 2: Publications

, 1967
Bimonthly magazine discussing topics related to aviation and model airplane engines including collecting, restoring, maintaining, and identifying engines, along with ...
The Model Museum, Dannels, Timothy J.
core +2 more sources

Reduced-Order Model for Bearingless PMSMs in Hardware-in-the-Loop

Energies
High production costs and extended development timelines pose significant challenges to the manufacturing of bearingless permanent magnet synchronous motors (BPMSMs). Moreover, uncertainties regarding the motor’s ability to generate suspension and torque
Lucas Selonke Klaas +2 more
doaj +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

Short-Term Control of Heat Pumps to Support Power Grid Operation

IEEE Open Journal of the Industrial Electronics Society
The increasing adoption of heat pumps presents new challenges for power grids, including the potential overloading of transformers and cables. To address this issue, in this work, a model predictive control for a low-temperature district heating network ...
Diran Liu +4 more
doaj +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source

Model Predictive Control of Aerial Manipulation via Hardware-in-the-Loop Simulation

IEEE Access
To perform aerial manipulation with an unmanned aerial vehicle (UAV), it is essential to develop countermeasures against dynamic disturbances affecting the UAV.
Jiwook Choi, Dongyoung Lee, Inho Lee
doaj +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

model-in-the-loop
hardware-in-the-loop
model predictive control

software in the loop
processor in the loop
hardware-in-the-loop hil

human-in-the-loop
hardware-in-the-loop simulation
model-based design