Results 91 to 100 of about 739,145 (318)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

One loop phenomenology of type II string theory: intersecting d-branes and noncommutativity [PDF]

open access: yes, 2007
We examine one loop amplitudes for open and closed strings in certain D-brane configurations, and investigate the consequences for phenomenology. Initially we consider open strings at D6-brane intersections.
Goodsell, Mark Dayvon   +1 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Integration of a mean-torque diesel engine model into a hardware-in-the-loop shipboard network simulation

open access: yes, 2010
This paper describes the creation of a hardware-in-the-loop demonstrator for use in evaluating network architecture and control concepts for marine electrical systems, as well as specific items of equipment.
Hill, J.E.   +8 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A Dynamic Operation Model for a Class of Closed-loop Logistic System

open access: yes, 2010
The operation process for a class of closed-loop logistic system is considered. This system contains multiple suppliers, manufactories, distribution centers and customers.
Xu Jiawang   +5 more
core   +1 more source

Gas Test Loop Booster Fuel Hydraulic Testing [PDF]

open access: yes, 2006
The Gas Test Loop (GTL) project is for the design of an adaptation to the Advanced Test Reactor (ATR) to create a fast-flux test space where fuels and materials for advanced reactor concepts can undergo irradiation testing.
Staff, Gas Test Loop Hydraulic Testing
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A note on loop-soliton solutions of the short-pulse equation

open access: yes, 2010
It is shown that the N-loop soliton solution to the short-pulse equation may be decomposed exactly into N separate soliton elements by using a Moloney-Hodnett type decomposition.
E.J. Parkes, Parkes, E.J.
core   +1 more source

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