Results 91 to 100 of about 739,145 (318)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
One loop phenomenology of type II string theory: intersecting d-branes and noncommutativity [PDF]
We examine one loop amplitudes for open and closed strings in certain D-brane configurations, and investigate the consequences for phenomenology. Initially we consider open strings at D6-brane intersections.
Goodsell, Mark Dayvon +1 more
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
This paper describes the creation of a hardware-in-the-loop demonstrator for use in evaluating network architecture and control concepts for marine electrical systems, as well as specific items of equipment.
Hill, J.E. +8 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A Dynamic Operation Model for a Class of Closed-loop Logistic System
The operation process for a class of closed-loop logistic system is considered. This system contains multiple suppliers, manufactories, distribution centers and customers.
Xu Jiawang +5 more
core +1 more source
Gas Test Loop Booster Fuel Hydraulic Testing [PDF]
The Gas Test Loop (GTL) project is for the design of an adaptation to the Advanced Test Reactor (ATR) to create a fast-flux test space where fuels and materials for advanced reactor concepts can undergo irradiation testing.
Staff, Gas Test Loop Hydraulic Testing
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A note on loop-soliton solutions of the short-pulse equation
It is shown that the N-loop soliton solution to the short-pulse equation may be decomposed exactly into N separate soliton elements by using a Moloney-Hodnett type decomposition.
E.J. Parkes, Parkes, E.J.
core +1 more source

