Results 21 to 30 of about 26,076,796 (269)
1st INCF Workshop on Genetic Animal Models for Brain Diseases [PDF]
, 2011 The INCF Secretariat organized a workshop to focus on the “role of neuroinformatics in the processes of building, evaluating, and using genetic animal models for brain diseases” in Stockholm, December 13–14, 2009.
Holm Graessner, Olaf Riess
core +2 more sources
Phase Diagrams of Quasispecies Theory with Recombination and Horizontal Gene Transfer
, 2006 We consider how transfer of genetic information between individuals influences the phase diagram and mean fitness of both the Eigen and the parallel, or Crow-Kimura, models of evolution.
J. Maynard +4 more
core +1 more source
Genetic and environmental links between self-reports and parent-reports of child personality [PDF]
, 2018 Personality ratings have been consistently found to be reliable and moderately heritable, but interrater agreement between self- and other-report of personality are low-to-moderate, particularly in childhood samples. The current study aims to examine the
Savicki, Stephanie Louise
core +1 more source
Determination of Nonlinear Genetic Architecture using Compressed Sensing
, 2015 We introduce a statistical method that can reconstruct nonlinear genetic models (i.e., including epistasis, or gene-gene interactions) from phenotype-genotype (GWAS) data.
Ho, Chiu Man, Hsu, Stephen D. H.
core +1 more source
Misspecification in mixed-model based association analysis
, 2015 Additive genetic variance in natural populations is commonly estimated using mixed models, in which the covariance of the genetic effects is modeled by a genetic similarity matrix derived from a dense set of markers.
Kruijer, Willem
core +2 more sources
Fused in sarcoma (FUS) inhibits milk production efficiency in mammals
Nature CommunicationsEfficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao +15 more
doaj +1 more source
Targeting cuproptosis by zinc pyrithione in triple-negative breast cancer
iScience, 2023 Summary: Triple-negative breast cancer (TNBC) poses a considerable challenge due to its aggressive nature. Notably, metal ion-induced cell death, such as ferroptosis, has garnered significant attention and demonstrated potential implications for cancer ...
Xu Yang +9 more
doaj +1 more source
Evolution in range expansions with competition at rough boundaries. [PDF]
, 2018 When a biological population expands into new territory, genetic drift develops an enormous influence on evolution at the propagating front. In such range expansion processes, fluctuations in allele frequencies occur through stochastic spatial wandering ...
Beller, Daniel A +3 more
core +2 more sources
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
Nature, 2014 Next-generation sequencing of human tumours has refined our understanding of the mutational processes operative in cancer initiation and progression, yet major questions remain regarding the factors that induce driver mutations and the processes that ...
Peter M. K. Westcott +13 more
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source