Results 21 to 30 of about 2,634,573 (271)
Genetic and environmental links between self-reports and parent-reports of child personality [PDF]
, 2018 Personality ratings have been consistently found to be reliable and moderately heritable, but interrater agreement between self- and other-report of personality are low-to-moderate, particularly in childhood samples. The current study aims to examine the
Savicki, Stephanie Louise
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Determination of Nonlinear Genetic Architecture using Compressed Sensing
, 2015 We introduce a statistical method that can reconstruct nonlinear genetic models (i.e., including epistasis, or gene-gene interactions) from phenotype-genotype (GWAS) data.
Ho, Chiu Man, Hsu, Stephen D. H.
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Fused in sarcoma (FUS) inhibits milk production efficiency in mammals
Nature CommunicationsEfficient milk production in mammals confers evolutionary advantages by facilitating the transmission of energy from mother to offspring. However, the regulatory mechanism responsible for the gradual establishment of milk production efficiency in mammals,
Haili Shao +15 more
doaj +1 more source
Statistical Modeling of Epistasis and Linkage Decay using Logic Regression [PDF]
, 2008 Logic regression has been recognized as a tool that can identify and model non-additive genetic interactions using Boolean logic groups. Logic regression, TASSEL-GLM and SAS-GLM were compared for analytical precision using a previously characterized ...
Jean-Luc Jannink +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Single-cell expression profiling of bat wing development
Nature CommunicationsBats are the only true-flight mammals, with wings formed by elongated digits and wing membranes. Despite the uniqueness, the cellular and molecular aspects of bat wing development remain largely unknown. Here, we use single-cell transcriptomic sequencing
Xue Lyu +7 more
doaj +1 more source
Metabolic Adaptation to Following Temperature Acclimation in Fish on the Yun-Gui Plateau
BiologyTemperature is crucial for fish physiology, as metabolism and related physiological processes are directly influenced by thermal energy. Against the backdrop of global warming, climate-induced variations in water temperature increasingly constrain fish ...
Wei Dao +9 more
doaj +1 more source
Misspecification in mixed-model based association analysis
, 2015 Additive genetic variance in natural populations is commonly estimated using mixed models, in which the covariance of the genetic effects is modeled by a genetic similarity matrix derived from a dense set of markers.
Kruijer, Willem
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CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]
, 2016 Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien +12 more
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Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source