Results 21 to 30 of about 1,214,603 (170)
Regional and aging-specific cellular architecture of non-human primate brains
Genome MedicineBackground Deciphering the functionality and dynamics of brain networks across different regions and age groups in non-human primates (NHPs) is crucial for understanding the evolution of human cognition as well as the processes underlying brain ...
Yun-Mei Wang +15 more
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Object-translocation induces event coding in the rat hippocampus
Communications BiologyEpisodic memory is the ability to recall personally experienced events that are situated within specific spatial contexts. Within a navigation environment, salient objects can function as landmarks, and interactions with them can be encoded as distinct ...
Ya-Li Duan +9 more
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A high-quality genome assembly of the Spectacled Fulvetta (Fulvetta ruficapilla) endemic to China
Scientific DataThe Spectacled Fulvetta (Fulvetta ruficapilla) is the type species of Fulvetta, an evolutionarily distinct group whose species show a high degree of sympatry in distribution and phenotypic convergence.
Chen Yan +6 more
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NEK4 modulates circadian fluctuations of emotional behaviors and synaptogenesis in male mice
Nature CommunicationsGWASs have linked the 3p21.1 locus, which is associated with the expression levels of NEK4, to bipolar disorder. Here, we use integrative analyses of GWAS statistics and eQTL annotations to establish that elevated NEK4 expression in the hippocampus is ...
Zhi-Hui Yang +13 more
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The nk model and population genetics [PDF]
Journal of Theoretical Biology, 2005 The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis. To examine these claims, an infinite-allele approximation is introduced.
John J. Welch, David Waxman
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Scientific DataStag beetles (Coleoptera: Lucanidae) represent a significant saproxylic assemblage in forest ecosystems and are noted for their enlarged mandibles and male polymorphism.
Xiaolu Li +8 more
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Multiscale spatial dependency of small mammal diversity patterns and their determinants
EcosphereAnimals perceive their ecosystems at multiple spatial scales such that the pattern–process relationships that determine their ecological and evolutionary opportunities are also spatially variable.
Kenneth Otieno Onditi +7 more
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Animal models with group-specific additive genetic variances: extending genetic group models [PDF]
Genetics Selection Evolution, 2018 Abstract1.Theanimal modelis a key tool in quantitative genetics and has been used extensively to estimate fundamental parameters, such as additive genetic variance, heritability, or inbreeding effects. An implicit assumption of animal models is that all founder individuals derive from a single population.
Stefanie Muff +5 more
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A Genetic Porcine Model of Cancer
PLOS ONE, 2015 The large size of the pig and its similarity in anatomy, physiology, metabolism, and genetics to humans make it an ideal platform to develop a genetically defined, large animal model of cancer. To this end, we created a transgenic "oncopig" line encoding Cre recombinase inducible porcine transgenes encoding KRASG12D and TP53R167H, which represent a ...
Eric M. Walters +12 more
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BMC BiologyBackground The tree shrew (Tupaia belangeri) is a promising emerging model organism in biomedical studies, notably due to their evolutionary proximity to primates.
Dongmin R. Son +5 more
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