Results 121 to 130 of about 26,891,998 (226)

The mean velocity of two-state models of molecular motor

, 2011
The motion of molecular motor is essential to the biophysical functioning of living cells. In principle, this motion can be regraded as a multiple chemical states process.
Bieling P., Howard J., Oster G., Udovichenko I. P., Wang H., Wang H., YUNXIN ZHANG, Zhang Y.   +7 more
core   +1 more source

What Genetic Modifications of Source Pigs Are Essential and Sufficient for Cell, Tissue, and Organ Xenotransplantation?

Transplant International
Xenotransplantation of porcine organs has made remarkable progress towards clinical application. A key factor has been the generation of genetically multi-modified source pigs for xenotransplants, protected against immune rejection and coagulation ...
Asghar Ali, Asghar Ali, Mayuko Kurome, Mayuko Kurome, Barbara Kessler, Barbara Kessler, Elisabeth Kemter, Elisabeth Kemter, Elisabeth Kemter, Elisabeth Kemter, Eckhard Wolf, Eckhard Wolf, Eckhard Wolf, Eckhard Wolf   +13 more
doaj   +1 more source

Global Collapses and Expansions in Star-Forming Clouds

, 2009
Spectral molecular line profile observations of star-forming molecular clouds sometimes show distinct red asymmetric double-peaked molecular line profiles with weaker blue peaks and stronger red peaks.
Adams, Adelson, Aguti, Arons, Belloche, Bernes, Bian, Carolan, Di Francesco, Evans, Fiege, Fiege, Fuller, Gao, Hammersley, Harvey, Hennebelle, Hogerheijde, Hu, Jørgensen, Kenyon, Keto, Lada, Larson, Lee, Lou, Lou, Lou, Lou, MacLow, Mardones, Matthews, Matzner, Matzner, McKee, Moraghan, Moriarty-Schieven, Myers, Myers, Nakano, Ossenkopf, Ostriker, Park, Park, Park, Rawlings, Redman, Redman, Saito, Schöier, Shang, Shen, Shirley, Shreider, Shu, Shu, Shu, Shu, Su, Tafalla, Tafalla, Tafalla, Thompson, Tsamis, van der Tak, Van Zadelhoff, Velusamy, Wang, Ward-Thompson, Wilner, Wu, Yang Gao, Yu, Yu, Yu-Qing Lou, Zhou, Zhou, Zweibel   +77 more
core   +1 more source

Model Selection and the Molecular Clock

PLoS Biology, 2006
A brief overview of the methods used to determine phylogenetic distances sets the stage for understanding new research published in PLoS Biology.
openaire   +4 more sources

Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer

Journal of Translational Medicine
Background Ovarian cancer (OC) is characterized by its rapid growth and spread which, accompanied by a low 5-year survival rate, necessitates the development of improved treatments.
Jing Guo, Xiaozhu Zeng, Yongjie Zhu, Dong Yang, Xudong Zhao   +4 more
doaj   +1 more source

ASS1 inhibits triple-negative breast cancer by regulating PHGDH stability and de novo serine synthesis

Cell Death and Disease
Argininosuccinate synthase (ASS1), a critical enzyme in the urea cycle, acts as a tumor suppressor in many cancers. To date, the anticancer mechanism of ASS1 has not been fully elucidated. Here, we found that phosphoglycerate dehydrogenase (PHGDH), a key
Wensong Luo, Zizheng Zou, Yuan Nie, Junli Luo, Zhengnan Ming, Xiyuan Hu, Tiao Luo, Min Ouyang, Mingquan Liu, Huicheng Tang, Yuanzhu Xie, Kunjian Peng, Ling Chen, Jiang Zhou, Zhiyong Luo   +14 more
doaj   +1 more source

PBMC-Humanized Mouse Model for Multiple Sclerosis: Studying Immune Changes and CNS Involvement

Bio-Protocol
Humanized immune system (HIS) mice are powerful tools for studying human immune system function and dysfunction and developing human-specific immunotherapeutics.
Anastasia Dagkonaki, Irini Papazian, Vasileios Gouzouasis, Ariadni Karles, Maria Kourouvani, Theodore Tselios, Eirini Fragkiadaki, Lesley Probert   +7 more
doaj   +1 more source

Epithelial–mesenchymal transition (EMT) and its role in acquired epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) chemoresistance in non-small cell lung cancer (NSCLC)

Cancer Pathogenesis and Therapy
Epithelial–mesenchymal transition (EMT) is a biological process that involves the transformation of epithelial cells into cells with a mesenchymal phenotype, enhancing their migratory and invasive capabilities.
Ma. Carmela P. Dela Cruz, Paul Mark B. Medina   +1 more
doaj  

Reply to "Molecular mechanics models for the image charge" [PDF]

, 2017
Barone, Bussi, Cicero, Fernández-Torre, Finnis, Hess, Hughes, Hughes, Iori, Iori, Kokh, Pensado, Phillips, Rosa, Spoel, Steinmann, Wright, Wright   +17 more
core   +1 more source

Cross-reactive CD8+ T cell responses to tumor-associated antigens (TAAs) and homologous microbiota-derived antigens (MoAs)

Journal of Experimental & Clinical Cancer Research
Background We have recently shown extensive sequence and conformational homology between tumor-associated antigens (TAAs) and antigens derived from microorganisms (MoAs).
Beatrice Cavalluzzo, Marie Christine Viuff, Siri Amanda Tvingsholm, Concetta Ragone, Carmen Manolio, Angela Mauriello, Franco M. Buonaguro, Maria Lina Tornesello, Francesco Izzo, Alessandro Morabito, Sine Reker Hadrup, Maria Tagliamonte, Luigi Buonaguro   +12 more
doaj   +1 more source