Results 101 to 110 of about 1,748,144 (308)

The prognostic importance of chronic end-stage diseases in geriatric patients admitted to 163 Italian ICUs [PDF]

, 2017
BACKGROUND: The number of elderly patients undergoing major surgical interventions and then needing admission to intensive care unit (ICU) grows steadily.
Alampi, Daniela, Bertolini, G., DE BLASI, Roberto Alberto, Finazzi, S., Giviti,, Gristina, G., Livigni, S., Malacarne, P., Mannoni, R., Nattino, G., Poole, D., Radrizzani, D., Sorgato, C   +12 more
core   +1 more source

Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling, Johannes P. van Dijk, Prisca R. Bauer, Roland D. Thijs, Josemir W. Sander, Machiel Zwarts, Gerhard H. Visser   +6 more
wiley   +1 more source

EEG Spectral Exponents and Visual Chirp Responses Mirror Anti‐Seizure Medication Load in Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Quantitative markers of cortical excitability may help identify responders to anti‐seizure medications (ASMs). We studied the relationship between ASM load and two electroencephalography (EEG) markers of cortical excitability in people with refractory epilepsy. Methods We included individuals with refractory focal epilepsy undergoing
Silvano R. Gefferie, Arthur R. van Nieuw Amerongen, Gerhard H. Visser, Maeike Zijlmans, Else A. Tolner, Mark van de Ruit, Arn M. J. M. van den Maagdenberg, Roland D. Thijs   +7 more
wiley   +1 more source

Current animal models of extracorporeal cardiopulmonary resuscitation: A scoping review

Resuscitation Plus, 2023
Aim: Animal models of Extracorporeal Cardiopulmonary Resuscitation (ECPR) focusing on neurological outcomes are required to further the development of this potentially life-saving technology.
Shinichi Ijuin, Keibun Liu, Denzil Gill, Sun Kyun Ro, Jana Vukovic, Satoshi Ishihara, Jan Belohlavek, Gianluigi Li Bassi, Jacky Y Suen, John F Fraser   +9 more
doaj  

Promoting the Responsible Development of Speech Datasets for Mental Health and Neurological Disorders Research [PDF]

Journal of Artificial Intelligence Research (JAIR), vol 82 (2025), pp 937-972
Current research in machine learning and artificial intelligence is largely centered on modeling and performance evaluation, less so on data collection. However, recent research demonstrated that limitations and biases in data may negatively impact trustworthiness and reliability.
arxiv   +1 more source

Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni, Paola Valsasina, Paolo Preziosa, Martina Rubin, Mor Gueye, Lucia Moiola, Maria Assunta Rocca, Massimo Filippi   +7 more
wiley   +1 more source

HPDL Variant Type Correlates With Clinical Disease Onset and Severity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee, Olivia Kim‐Mcmanus, Jennifer H. Yang, Richard Haas, Maha S. Zaki, Ghada M. H. Abdel‐Salam, Yuji Nakamura, Mohamed S. Abdel‐Hamind, Darius Ebrahimi‐Fakhari, Julian E. Alecu, Nicola Brunetti‐Pierri, Varunvenkat M. Srinivasan, Vykuntaraju K. Gowda, Stephanie Gross, Yasemin Alanay, Paria Najarzadeh Totbati, Manya Yadavilli, Liana Friedman, Naomi Meave Ojeda, Joseph G. Gleeson   +19 more
wiley   +1 more source

Investigating the Unmet Need and Future of Neurorehabilitation in India: A Scoping Review [PDF]

Iranian Rehabilitation Journal
Objectives: This study explores the challenges of implementing physical rehabilitation for people with neurological diseases at in-hospital and community levels in India, summarizes the unmet needs of evidence-based physical neurorehabilitation in India,
Dorcas B C Gandhi, Ivy A Sebastian, Amreen Mahmood, Pradeepa Nayak, Mridul Makkar, Dimple Dawar, Nistara S Chawla, Jeyaraj Durai Pandian   +7 more
doaj  

Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage. [PDF]

, 2017
BACKGROUND: Injury to cells adjacent to an intracerebral hemorrhage (ICH) is likely mediated at least in part by toxins released from the hematoma that initiate complex and interacting injury cascades.
Chen-Roetling, Jing, Regan, Raymond F.
core   +1 more source

Modeling the Neurologic and Cognitive Effects of Hyponatremia [PDF]

Journal of the American Society of Nephrology, 2016
Acute hyponatremia causes swelling of brain cells and, if of a sufficient degree, increased intracranial pressure. This is a consequence of the relative impermeability of the blood-brain barrier to sodium ions[1][1]; this principle underlies the clinical utility of hypertonic NaCl infusion in ...
openaire   +3 more sources