Brain Organoids: Filling the Need for a Human Model of Neurological Disorder
Biology, 2021 Neurological disorders are among the leading causes of death worldwide, accounting for almost all onsets of dementia in the elderly, and are known to negatively affect motor ability, mental and cognitive performance, as well as overall wellbeing and ...
Philip Jalink, Massimiliano Caiazzo
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Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research. [PDF]
, 2017 Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size.
Akyol, Onat +6 more
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Enhancing Nervous System Recovery through Neurobiologics, Neural Interface Training, and Neurorehabilitation. [PDF]
, 2016 After an initial period of recovery, human neurological injury has long been thought to be static. In order to improve quality of life for those suffering from stroke, spinal cord injury, or traumatic brain injury, researchers have been working to ...
Edgerton, V Reggie +4 more
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Early motor trajectories predict motor but not cognitive function in preterm- and term-born adults without pre-existing neurological conditions [PDF]
, 2020 Very preterm (VP; 0.05). Motor problems in childhood were homotypically associated with poorer motor competence in adulthood. Similarly, early cognitive problems were homotypically associated with adult cognitive outcomes. Thus, both motor and cognitive
Bartmann, Peter +3 more
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Extended Timed Up and Go assessment as a clinical indicator of cognitive state in Parkinson\u27s disease [PDF]
, 2017 Objective: To evaluate a modified extended Timed Up and Go (extended-TUG) assessment against a panel of validated clinical assessments, as an indicator of Parkinson’s disease (PD) severity and cognitive impairment. Methods: Eighty-seven participants with
Anderton, R +7 more
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Molecular Targets of Cannabidiol in Experimental Models of Neurological Disease
Molecules, 2020 Cannabidiol (CBD) is a non-psychoactive phytocannabinoid known for its beneficial effects including antioxidant and anti-inflammatory properties. Moreover, CBD is a compound with antidepressant, anxiolytic, anticonvulsant and antipsychotic effects ...
Serena Silvestro +3 more
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Current animal models of extracorporeal cardiopulmonary resuscitation: A scoping review
Resuscitation Plus, 2023 Aim: Animal models of Extracorporeal Cardiopulmonary Resuscitation (ECPR) focusing on neurological outcomes are required to further the development of this potentially life-saving technology.
Shinichi Ijuin +9 more
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Experimental Animal Models in Neurological Diseases
Düzce Tıp Fakültesi DergisiThe human brain is a structure that controls billions of neurons and trillions of connections. Having a unique anatomy with countless neurons and connections makes its understanding even more complex.
Neslihan Şirin, Şerif Demir
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Noise in multiple sclerosis: unwanted and necessary [PDF]
, 2014 As our knowledge about the etiology of multiple sclerosis (MS) increases, deterministic paradigms appear insufficient to describe the pathogenesis of the disease, and the impression is that stochastic phenomena (i.e.
BORDI, Isabella +7 more
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Porcine Models of Neurotrauma and Neurological Disorders
BiomedicinesThe translation of therapeutics from lab to clinic has a dismal record in the fields of neurotrauma and neurological disorders [...]
John C. O’Donnell, Dmitriy Petrov
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